Results 1 to 10 of about 3,825 (129)

Terbinafine Resistance in Dermatophytes: A French Multicenter Prospective Study [PDF]

Journal of Fungi, 2022
In recent years, we have moved from the sporadic description of terbinafine-resistant (TerR) Trichophyton spp. isolates to the Indian outbreak due to T. indotineae. Population flows have spread TerR worldwide, altering local epidemiology.
Alicia Moreno-Sabater, Anne-Cécile Normand, Anne-Laure Bidaud, Geneviève Cremer, Françoise Foulet, Sophie Brun, Christine Bonnal, Nawel Aït-Ammar, Arnaud Jabet, Aymen Ayachi, Renaud Piarroux, Françoise Botterel, Sandrine Houzé, Guillaume Desoubeaux, Christophe Hennequin, Eric Dannaoui   +15 more
doaj   +4 more sources

Increasing Terbinafine Resistance in Danish Trichophyton Isolates 2019–2020 [PDF]

Journal of Fungi, 2022
Terbinafine resistance in Trichophyton species has emerged and appears to be increasing. A new EUCAST susceptibility testing method and tentative ECOFFs were recently proposed for Trichophyton.
Karen Marie Thyssen Astvad, Rasmus Krøger Hare, Karin Meinike Jørgensen, Ditte Marie Lindhardt Saunte, Philip Kjettinge Thomsen, Maiken Cavling Arendrup   +5 more
doaj   +2 more sources

Increased copy number of the target gene squalene monooxygenase as the main resistance mechanism to terbinafine in Leishmania infantum

International Journal for Parasitology: Drugs and Drug Resistance, 2023
We use here two genomic screens in an attempt to understand the mode of action and resistance mechanism of terbinafine, an antifungal contemplated as a potential drug against the parasite Leishmania.
Jade-Éva Potvin, Fereshteh Fani, Marine Queffeulou, Élodie Gazanion, Philippe Leprohon, Marc Ouellette   +5 more
doaj   +3 more sources

National Belgian Study on Terbinafine Resistance in Trichophyton interdigitale/mentagrophytes/indotineae (2022–2023): Epidemiology and Molecular Features [PDF]

Journal of Fungi
Objectives: Trichophyton indotineae, a dermatophyte closely related to T. interdigitale and T. mentagrophytes, is of growing concern due to its high terbinafine resistance and widespread presence in India.
Rosalie Sacheli, Sabrina Egrek, Khalid El Moussaoui, Bahoz Kurt, Emilie Machowski, Saadia Harag, Marie-Pierre Hayette   +6 more
doaj   +2 more sources

Molecular Characterization and Preliminary NGS Profiling of Terbinafine-Resistant Trichophyton indotineae Isolates in Italy [PDF]

Pathogens
Trichophyton indotineae is an emerging dermatophyte associated with extensive, chronic, recalcitrant, and frequently terbinafine-resistant dermatophytosis worldwide. In this study, 30 T. indotineae strains isolated in Italy were investigated.
Deborah Cruciani, Manuela Papini, Luigi Pisano, Roberta Calcaterra, Donatella Pietrella, Tommaso Galeotti, Paolo Fazii, Antonia Meloscia, Martina Torricelli, Marco Di Domenico, Alessandro Fiorucci, Sara Spina, Silvia Crotti   +12 more
doaj   +2 more sources

Computational analysis of missense mutations in squalene epoxidase associated with terbinafine resistance in clinically reported dermatophytes [PDF]

Scientific Reports
Dermatophyte infections, as a significant public health threats, are increasingly associated with antifungal drug resistance, particularly to terbinafine.
Hussein R. Mahmood, Masoomeh Shams-Ghahfarokhi, Mehdi Razzaghi-Abyaneh   +2 more
doaj   +2 more sources

Terbinafine Resistance in Trichophyton rubrum and Trichophyton indotineae: A Literature Review [PDF]

Antibiotics
Background/Objectives: Terbinafine has been the gold standard for the management of superficial fungal infections. The etiological agent generally is Trichophyton rubrum (T.
Aditya K. Gupta, Susmita, Hien C. Nguyen, Amanda Liddy, Vasiliki Economopoulos, Tong Wang   +5 more
doaj   +2 more sources

Sensitivity of Dermatophytes to Terbinafine: World Experience and Recent Findings from Kazakhstan [PDF]

Antibiotics
Background/Objectives: This article describes the results of an analysis of the sensitivity of dermatophytosis pathogens to terbinafine, conducted by the authors based on a review of available scientific publications and data from their own research ...
Alma Aimoldina, Ainura Smagulova, Yelena Kukhar, Gulnar Batpenova, Togzhan Algazina, Rabiga Uakhit, Vladimir Kiyan   +6 more
doaj   +2 more sources

Isolation of Terbinafine-Resistant Trichophyton rubrum from Onychomycosis Patients Who Failed Treatment at an Academic Center in New York, United States

Journal of Fungi, 2023
Onychomycosis is a common nail infection. Terbinafine-resistant dermatophyte infections pose an emerging global public health concern, but few cases have been described in the United States.
Jonathan K. Hwang, Wayne L. Bakotic, Jeremy A. W. Gold, Cynthia M. Magro, Shari R. Lipner   +4 more
doaj   +1 more source

Green Microalgae Strain Improvement for the Production of Sterols and Squalene

Plants, 2021
Sterols and squalene are essential biomolecules required for the homeostasis of eukaryotic membrane permeability and fluidity. Both compounds have beneficial effects on human health. As the current sources of sterols and squalene are plant and shark oils,
Supakorn Potijun, Suparat Jaingam, Nuttha Sanevas, Srunya Vajrodaya, Anchalee Sirikhachornkit   +4 more
doaj   +1 more source