Results 41 to 50 of about 2,324,813 (189)

In vitro activities of antifungal agents alone and in combination against fluconazole-susceptible and -resistant strains of Candida dubliniensis

open access: yesBrazilian Journal of Infectious Diseases, 2012
In the present study we used two groups of Candida dubliniensis strains: one containing fluconazole-susceptible clinical isolates and another containing fluconazole-resistant laboratory derivative from the former to examine the changes on susceptibility ...
Liliane Alves Scheid   +4 more
doaj   +1 more source

Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide, [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2021
Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery ...
Marcelo Rosandiski Lyra   +3 more
doaj   +1 more source

Photodynamic therapy: A treatment option for terbinafine resistant Trichophyton species

open access: yesPhotodiagnosis and Photodynamic Therapy, 2021
Terbinafine is a first-line agent against Trichophyton-infections. However, treatment failure and resistance due to squalene epoxidase (SQLE) alterations are increasingly being reported. Photodynamic therapy (PDT) is based on combining a photosensitizer, light and oxygen to create photo-activated reactive oxygen species.
Julia J. Shen   +3 more
openaire   +3 more sources

Trichophyton indotineae—An Emerging Pathogen Causing Recalcitrant Dermatophytoses in India and Worldwide—A Multidimensional Perspective

open access: yesJournal of Fungi, 2022
Trichophyton (T.) indotineae is a newly identified dermatophyte species that has been found in a near-epidemic form on the Indian subcontinent. There is evidence of its spread from the Indian subcontinent to a number of countries worldwide. The fungus is
Silke Uhrlaß   +6 more
doaj   +1 more source

Terbinafine resistance mediated by salicylate 1-monooxygenase in Aspergillus nidulans

open access: yes, 2004
Resistance to antifungal agents is a recurring and growing problem among patients with systemic fungal infections. UV-induced Aspergillus nidulans mutants resistant to terbinafine have been identified, and we report here the characterization of one such ...
Rocha, Eleusa M. F.   +3 more
core   +1 more source

Detailed Mechanism of Squalene Epoxidase Inhibition by Terbinafine

open access: yes, 2016
Squalene epoxidase (SE) is a key flavin adenine dinucleotide (FAD)-dependent enzyme of ergosterol and cholesterol biosynthetic pathways and an attractive potential target for drugs used to inhibit the growth of pathogenic fungi or to lower cholesterol ...
Piotr Stepniak (2228593)   +7 more
core   +4 more sources

In Vitro Analysis of the Ability of Trichophyton rubrum To Become Resistant to Terbinafine [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2003
ABSTRACT In this study, we have investigated in vitro the resistance frequency and development of resistance to terbinafine of Trichophyton rubrum . Results demonstrated that naturally occurring mutants are rare and that T.
Osborne, C. S.   +3 more
openaire   +3 more sources

Not Just Mycosis Fungoides: A Case Series of Concurrent Fungal Infections in Patients With Cutaneous T‐Cell Lymphoma

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Mycosis fungoides is a misnomer that means ‘mushroom‐like fungal disease’, but it is, in fact, the most common form of cutaneous T‐cell lymphoma. The diagnosis of mycosis fungoides is often delayed due to non‐specific symptoms and cutaneous signs that mimic other common benign inflammatory dermatoses.
Ji Fung Yong   +5 more
wiley   +1 more source

Amino acid substitution in Trichophyton rubrum squalene epoxidase associated with resistance to terbinafine.

open access: yes, 2005
There has only been one clinically confirmed case of terbinafine resistance in dermatophytes, where six sequential Trichophyton rubrum isolates from the same patient were found to be resistant to terbinafine and cross-resistant to other squalene ...
Leitner, Ingrid   +7 more
core   +1 more source

Efficacy and safety of terbinafine 500 mg once daily in patients with dermatophytosis

open access: yesIndian Journal of Dermatology, 2017
Introduction: Dermatophytosis are the most common fungal infections globally. Terbinafine is considered to have good potency against dermatophytes, but resistance to terbinafine is on the rise.
P Ravindra Babu   +5 more
doaj   +1 more source

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