Results 61 to 70 of about 4,050 (165)
Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro +2 more
wiley +1 more source
Anti-fungal Resistance Threats in Dermatophytosis : A Literature Review
Background: In recent years, antifungal resistance in dermatophytosis has escalated, observed not only in the endemic regions of India but also across East Asia, the Americas, and Europe.
Ida Ayu Made Niki Putri Ashrita +1 more
doaj +1 more source
This review highlights the synthesis of chitosan nanoparticles from natural sources, the thorough characterization of them, and use of microscopic and spectroscopic methods. It emphasizes that it has some indispensable properties such as being non‐toxic, antimicrobial, and capable of controlled drug release.
Mariam Sohail Mansoor +6 more
wiley +1 more source
Clinical Trichophyton rubrum Strain Exhibiting Primary Resistance to Terbinafine [PDF]
ABSTRACT The in vitro antifungal susceptibilities of six clinical Trichophyton rubrum isolates obtained sequentially from a single onychomycosis patient who failed oral terbinafine therapy (250 mg/day for 24 weeks) were determined by broth microdilution and macrodilution methodologies.
Pranab K, Mukherjee +5 more
openaire +2 more sources
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni +6 more
wiley +1 more source
Metabolism in Tumor: Mechanisms and Therapeutic Perspectives
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng +6 more
wiley +1 more source
Background: The rising incidence of resistant fungal infections poses significant therapeutic challenges. This study aimed to compare the efficacy and safety of terbinafine monotherapy versus combination therapy with terbinafine and voriconazole in patients with resistant fungal infections.
Dr. Farjana Akhter +2 more
openaire +1 more source
In this work, a number of chromenoquinolines were synthesized in an aqueous medium at room temperature using isinglass–bassorin (IG‐BR) cryogel as an eco‐friendly heterogeneous catalyst. Furthermore, when tested for antifungal efficacy in vitro against three different kinds of fungal infections, all target compounds showed better inhibitory zones than ...
Shahrzad Abdolmohammadi +3 more
wiley +1 more source
Recent Findings in Onychomycosis and Their Application for Appropriate Treatment
Onychomycosis is mainly caused by two dermatophyte species, Trichophyton rubrum and Trichophyton interdigitale. A study of nail invasion mechanisms revealed that the secreted subtilisin Sub6, which has never been detected under in vitro growth conditions,
Michel Monod, Bruno Méhul
doaj +1 more source

