Results 71 to 80 of about 3,875 (165)

Successful Use of Bimekizumab in Refractory Acute Generalised Exanthematous Pustulosis Triggered by Amoxicillin‐Clavulanate

JEADV Clinical Practice, Volume 5, Issue 2, Page 669-672, June 2026.
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge, Charlotte Vogel, Theresa Hempel, Basil Signer, Nikhil Yawalkar, Kristine Heidemeyer   +5 more
wiley   +1 more source

Recent Findings in Onychomycosis and Their Application for Appropriate Treatment

Journal of Fungi, 2019
Onychomycosis is mainly caused by two dermatophyte species, Trichophyton rubrum and Trichophyton interdigitale. A study of nail invasion mechanisms revealed that the secreted subtilisin Sub6, which has never been detected under in vitro growth conditions,
Michel Monod, Bruno Méhul
doaj   +1 more source

Patterns of culture positivity and antifungal sensitivity in dermatophytosis

MGM Journal of Medical Sciences, 2019
Background: Antifungal drug resistance and a lack of clinical response in 20% of cases of dermatophytosis calls for an evaluation of resistant dermatophytes using a standardized simple and reproducible in vitro assay, to allow clinician to select the ...
Vedant Ghuse, Shylaja Someshwar, Hemangi Jerajani   +2 more
doaj   +1 more source

In vitro susceptibility profiles of 16 antifungal drugs against Trichophyton indotineae

Microbiology Spectrum
The worldwide emergence of Trichophyton indotineae has garnered significant attention due to its growing resistance to conventional antifungal therapies, posing significant challenges to the effective management of dermatophytosis.
Wenting Xie, Xue Kong, Hailin Zheng, Huan Mei, Naicen Ge, Weida Liu, Guanzhao Liang, Xiaofang Li   +7 more
doaj   +1 more source

Epidemiology and Molecular Identification of Dermatophytes: Focus on the Detection of the Emerging Species Trichophyton indotineae in Northern Italy

Microbiology Research
Background: Trichophyton indotineae, a new emerging pathogen according to the WHO, is known to cause severe forms of tinea. Given that traditional identification methods rely on morphological characteristics, and the morphological distinctions among T ...
Valentina Lepera, Gabriella Tocci, Giorgia Palladini, Marco Enrico Giovanni Arosio, Claudio Farina, Giuliana Lo Cascio, on behalf of the Medical Mycology Committee (CoSM)—Italian Association of Clinical Microbiology (AMCLI)   +6 more
doaj   +1 more source

Is antifungal resistance a cause for treatment failure in dermatophytosis: A study focused on tinea corporis and cruris from a tertiary centre?

Indian Dermatology Online Journal, 2018
Background: Dermatophytoses are one of the most common skin diseases that have been largely simple to treat. However, in recent years, these infections have become recalcitrant to treatment which can possibly be due to antifungal resistance.
Kabir Sardana, Ravinder Kaur, Pooja Arora, Ritu Goyal, Sneha Ghunawat   +4 more
doaj   +1 more source

Evaluation of Gradient Concentration Strips for Detection of Terbinafine Resistance in Trichophyton spp. [PDF]

Antimicrob Agents Chemother, 2023
Bidaud AL, Moreno-Sabater A, Normand AC, Cremer G, Foulet F, Brun S, Ayachi A, Imbert S, Chowdhary A, Dannaoui E.   +9 more
europepmc   +1 more source

Epidemiology and Genomic Characterization of Trichophyton mentagrophytes over a Period of 4 Years in Northern Italy

Journal of Fungi
Dermatophytes are keratinophilic fungi that cause a wide range of superficial infections in humans and animals. The Trichophyton mentagrophytes species complex is one of the most clinically important groups due to its broad host range, widespread ...
Luca Rossi, Annarita Sorrentino, Caterina Signoretto, Paolo Gaibani   +3 more
doaj   +1 more source

Mechanisms of resistance against allylamine and azole antifungals in Trichophyton: A renewed call for innovative molecular diagnostics in susceptibility testing.

PLoS Pathogens
The emergence of antifungal resistance calls for continued research efforts to better guide healthcare providers in treatment selection and outcomes. Unlike bacterial infections, treatment of superficial fungal infections is mainly limited to allylamines
Aditya K Gupta, Tong Wang, Avantika Mann, Vincent Piguet, Anuradha Chowdhary, Wayne L Bakotic   +5 more
doaj   +1 more source

Resistance and Recalcitrance in Dermatophytosis: Mechanistic and Clinical Considerations for Keratinized Tissues

Antibiotics
Dermatophytosis remains one of the most prevalent superficial fungal infections worldwide and is increasingly encountered as a persistent or difficult-to-treat syndrome.
Alfredo Valdez-Martinez, Roberto Arenas, Andrea Moreno-Salinas, Mariana Perez-Tristan, Maria Jose Gomez-Rico, Ivette Torres-Olguín, Claudia Erika Fuentes-Venado, Fernando Bastida-González, Erick Martínez-Herrera, Rodolfo Pinto-Almazán   +9 more
doaj   +1 more source