Results 51 to 60 of about 14,886 (208)

Limited Activity Of Miltefosine In Murine Models Of Cryptococcal Meningoencephalitis And Disseminated Cryptococcosis [PDF]

, 2013
Miltefosine is an alkyl phosphocholine with good oral bioavailability and in vitro activity against Cryptococcus species that has gained interest as an additional agent for cryptococcal infections.
Bocanegra, Rosie, Kirkpatrick, William R., Najvar, Laura K., Patterson, Thomas F., Sorrell, Tania C., Wiederhold, Nathan P.   +5 more
core   +1 more source

Synergistic effect of terbinafine and amphotericin B in killing Fonsecaea nubica in vitro and in vivo

Revista do Instituto de Medicina Tropical de São Paulo
Chromoblastomycosis is a chronic fungal infection. Itraconazole and terbinafine are the most recommended antifungal drugs for chromoblastomycosis, while amphotericin B is not usually recommended.
Jing Zhang, Xiaoyan Wu, Meirong Li, Jiamin Huang, Songchao Yin, Huaiqiu Huang, Chun Lu, Liyan Xi   +7 more
doaj   +1 more source

Terbinafine versus itraconazole: a long-term, randomized, double-blind, clinical trial in chronic pulmonary aspergillosis. A pilote study [PDF]

Journal of Health and Social Sciences, 2016
Background: The frequency of pulmonary aspergillosis has been increasing for decades. Standard oral treatment is associated with tolerability problems and interactions with commonly used medications.
Gianfranco Schiraldi, Salvatore Lo Cicero, Claudio Rossetti, Delia Colombo, Michele Chiericozzi, Elvana Kola, Luigi Allegra   +6 more
doaj   +1 more source

Fungal Translocation Marker in People Living with HIV Needing Treatment for Onychomycosis: A Protocol for the Prospective Pilot Study

Infectious Diseases & Immunity, 2022
. Increased microbial translocation and chronic immune activation are two critical problems for people living with HIV (PLWH) in the antiretroviral therapy (ART) era.
Yaling Chen, Jing Ouyang, Stéphane Isnard, Cecilia T. Costiniuk, Jiangyu Yan, Xin Zhou, Jean-Pierre Routy, Yaokai Chen, Wei Zhao   +8 more
doaj   +1 more source

Multicenter, International Study of MIC/ MEC Distributions for definition of epidemiological cutoff values for sporothrix species identified by molecular methods [PDF]

, 2017
Clinical and Laboratory Standards Institute (CLSI) conditions for testing the susceptibilities of pathogenic Sporothrix species to antifungal agents are based on a collaborative study that evaluated five clinically relevant isolates of Sporothrix ...
Abreu, D.P.B., Almeida-Paes, R., Ballesté Alaniz, R., Bonfietti, L.X., Bonifaz, A., Brilhante, R.S.N., Chakrabarti, A., Chowdhary, A., Córdoba, S., Espinel-Ingroff, A., et al., Gonzalez, G.M., Govender, N.P., Guarro, J., Hagen, F., Johnson, E.M., Kidd, S., Pereira, S.A., Rodrigues, A.M., Rozental, S., Szeszs, M.W.   +20 more
core   +1 more source

Evaluation of efficacy and safety of topical 1% terbinafine versus topical 2% sertaconazole in patients with tinea cruris – A randomized controlled trial

National Journal of Physiology, Pharmacy and Pharmacology, 2021
Background: Dermatophyte infections are very common and they manifest as tinea corporis/cruris. Among the various topical antifungal drugs available, the first option being terbinafine and new generation azoles as sertaconazole professes superior ...
Meghana D, Laxminarayana Kamath, Revathi T N   +2 more
doaj   +1 more source

Photodynamic Therapy Combined with Terbinafine Against Chromoblastomycosis and the Effect of PDT on Fonsecaea monophora In Vitro [PDF]

, 2014
Chromoblastomycosis, a chronic fungal infection of skin and subcutaneous tissue caused by dematiaceous fungi, is associated with low cure and high relapse rates. Among all factors affecting clinical outcome, etiological agents have an important position.
Hamblin, Michael R, Hu, Yongxuan, Huang, Xiaowen, Lu, Sha, Mylonakis, Eleftherios, Xi, Liyan, Zhang, Junmin   +6 more
core   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

A comparative study of efficacy and safety of oral griseofulvin versus oral terbinafine in patients with tinea capitis at a tertiary care hospital

National Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Tinea capitis is a common dermatophytic infection of the scalp hair follicle and the intervening skin with an incidence in rural India of about 28.5%. Antifungal agent terbinafine which requires a shorter course of treatment than conventional
Geetha A, Ramya Y S, Divakar, Raghav M V
doaj   +1 more source

Recurrent Scedosporium apiospermum mycetoma successfully treated by surgical excision and terbinafine treatment: a case report and review of the literature [PDF]

, 2017
Background: Scedosporium apiospermum is an emerging opportunistic filamentous fungus, which is notorious for its high levels of antifungal ‑resistance.
A Harun, C Eldin, CH Chiang, CH Heath, CP Bower, Csaba Vágvölgyi, D Reimann, E Lemerle, Edit Urbán, Eszter J. Tóth, F Beier, F Bosma, F Gilgado, G Béraud, G Tarozzi, Gábor Nagy, Géza R. Nagy, I Tammer, I Tammer, I Valenzuela Salas, Ildikó É. Kiss, J Guarro, J Sopta, JV Pether, KJ Cortez, L Ajello, L Porte, L Török, LA Montero, Lajos Kemény, M Chen, M Lainščak, M Montejo, Marianna Ábrók, MI Taşbakan, Mónika Homa, PG Rogasi, R Cunningham, R Horré, S Giraud, SA Kantarcioğlu, Tamás Papp, TJ White, TT Ng, V Gulati, Zsuzsanna Bata-Csörgő   +45 more
core   +1 more source