Results 61 to 70 of about 7,428 (160)

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2682-2692, August 2026.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup   +2 more
wiley   +1 more source

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino   +10 more
wiley   +1 more source

An Unusual Case of Nannizzia praecox – Infection with new observations on the pathogen

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina Antonia Langen   +3 more
wiley   +1 more source

Probiotic Engraftment and Suppression of Canine Otitis Externa Pathogens by Probiotic Ear Drops

open access: yesVeterinary Dermatology, Volume 37, Issue 4, Page 534-540, August 2026.
Background: Lactobacillaceae have shown promise with their potential to outcompete pathogens and restore a healthy microbial balance in otitis externa (OE). Hypothesis/Objectives: This study aimed to evaluate the presence of viable Lactobacillaceae over time and in vitro ability to inhibit the growth of common OE pathogens.
Marta Salichs   +6 more
wiley   +1 more source

Relapse after oral terbinafine therapy in dermatophytosis: A clinical and mycological study

open access: yesIndian Journal of Dermatology, 2016
Background: The incidence of recurrent tinea infections after oral terbinafine therapy is on the rise. Aim: This study aims to identify the appearance of incomplete cure and relapse after 2-week oral terbinafine therapy in tinea corporis and/or tinea ...
Imran Majid   +3 more
doaj   +1 more source

A Week of Oral Terbinafine Pulse Regimen Every Three Months to Treat all Dermatophyte Onychomycosis

open access: yesJournal of Fungi, 2019
Terbinafine has proved to treat numerous fungal infections, including onychomycosis, successfully. Due to its liver metabolization and dependency on the cytochrome P450 enzyme complex, undesirable drug interaction are highly probable.
Anarosa B. Sprenger   +3 more
doaj   +1 more source

Bilateral Ulcers in Protothecosis: A Diagnostic Challenge

open access: yes
International Journal of Dermatology, Volume 65, Issue 9, Page 1926-1928, September 2026.
Waratchaya Panjapakkul   +4 more
wiley   +1 more source

Antibiofilm Activity of Fluconazole/Terbinafine Combination in Candida albicans HWP1 Gene Expression [PDF]

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2018
Background: Biofilm formation represents one of the major virulence factors of Candida albican. However, the number of antifungal drugs is limited for the treatment of candidiasis.
Alireza Khodavandi   +2 more
doaj  

MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES

open access: yesАрхивъ внутренней медицины, 2016
Close clinical and phylogenetic relationship of skin conditions, mental health and disorders of the hepatobiliary system was established. The aim of the study was to evaluate the efficacy of systemic antifungal monotherapy (terbinafine) plus S ...
E. V. Gerasimchuk   +2 more
doaj   +1 more source

Gelatin Nanoemulsion-Based Co-Delivery of Terbinafine and Essential Oils for Treatment of Candida albicans Biofilms

open access: yesMicroorganisms
Fungal infections represent a significant global health challenge. Candida albicans is a particularly widespread pathogen, with both molecular and biofilm-based mechanisms making it resistant to or tolerant of available antifungal drugs.
Muhammad Aamir Hassan   +6 more
doaj   +1 more source

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