Results 151 to 160 of about 56,596 (269)

“Hedgehog pathway”: a potential target of itraconazole in the treatment of cancer

Journal of Cancer Research and Clinical Oncology, 2020
Xin Wei, Wu Liu, Jia-Qi Wang, Ze-Yao Tang   +3 more
semanticscholar   +1 more source

Sterol composition of itraconazole-resistant and itraconazole-susceptible isolates of Aspergillus fumigatus

, 2001
Sterol composition of four clinical isolates of Aspergillus fumigatus resistant to itraconazole was determined by gas chromatography – mass spectrometry and compared with that of four susceptible strains. For all strains, the major sterol was ergosterol.
Eric Dannaoui, Stéphane Picot, Elisabeth Borel, Florence Persat, Marie-Antoinette Piens   +4 more
core   +1 more source

Pancreatitis associated with the use of itraconazole

, 2010
BACKGROUND: We call attention to the assumed association between itraconazole and pancreatitis by presentation of four Dutch case reports.METHODS AND RESULTS: The Netherlands Pharmacovigilance Centre Lareb received four reports of pancreatitis associated
van Puijenbroek, E P; id_orcid, van Grootheest, A C, Passier, J L M, Jonkers, G J P M   +3 more
core   +2 more sources

Practical recommendations for seborrheic dermatitis management: An expert consensus

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 9, Page 1460-1468, September 2026.
This modified Delphi study established expert consensus on Seborrheic Dermatitis management. Key findings prioritize combined topical antifungal and anti‐inflammatory therapy for both acute flares and long‐term maintenance. The consensus also provides a clear framework for escalating to systemic treatment in extensive or refractory cases.
L. Naldi, A. Kyrgidis, G. S. Tiplica, M. A. de Rie, D. Tatsis, P. Gisondi, D. Ioannides, O. Chosidow, M. Deleuran, the Delphi SD study experts   +9 more
wiley   +1 more source

The ER–Golgi Lipid Exchanger PsORP1 Is Essential for Phytophthora sojae Development and Is Blocked by Oxathiapiprolin via Its OSBP‐Related Domain (ORD)

Molecular Plant Pathology, Volume 27, Issue 9, September 2026.
PsORP1 anchors ER–Golgi MCSs to mediate PS/PI4P counter‐transport, and oxathiapiprolin targets the ORD to inhibit this lipid exchange. ABSTRACT Oxysterol‐binding protein (OSBP)‐related proteins (ORPs) are indispensable eukaryotic lipid transporters and promising targets for pharmaceutical and agrochemical exploitation.
Xiaofei Liu, Chengcheng Li, Guangda Shao, Qin Peng, Haixia Wang, Jianqiang Miao, Xili Liu   +6 more
wiley   +1 more source

Pulmonary aspergilloma: a treatment challenge in sub-saharan Africa. [PDF]

, 2013
Jugheli, Levan, Said, Khadija, Fredrick Haraka, Klaus Reither, Pohl, Christian, Reither, Klaus, Levan Jugheli, Elirehema Mfinanga, Mfinanga, Elirehema, Khadija Said, Haraka, Fredrick, Christian Pohl   +11 more
core   +2 more sources

Antifungal Susceptibility Profile and Biocide Tolerance in Clinically Relevant Yeasts: Implications for Therapy and Hospital Infection Control

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Background Opportunistic yeasts account for a substantial proportion of invasive fungal infections and are important agents of healthcare‐associated infections, especially in intensive care units (ICUs). Objectives To describe the clinical and epidemiological characteristics of hospitalized patients with positive cultures for medically ...
Yasmim Passos Lima, Letícia Rebello Machado, Ricardo Villela Bastos, Victor Quinet de Andrade Bastos, Lucas Quinet de Andrade Bastos, André Netto Bastos, Claudio Galuppo Diniz, Vania Lúcia da Silva, Vanessa Cordeiro Dias   +8 more
wiley   +1 more source

Three‐Dimensional Airway Reconstruction and Computational Spray Simulation to Guide Bronchoscopic Amphotericin B Delivery in Chronic Pulmonary Aspergillosis: An Exploratory Prospective Cohort Study With Historical Controls

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Objective To initially evaluate the feasibility and potential clinical value of high‐resolution computed tomography (HRCT)‐based three‐dimensional (3D) airway reconstruction combined with computational spray simulation for guiding bronchoscopic amphotericin B delivery in patients with chronic pulmonary aspergillosis (CPA).
Yonghui Cheng, Hao Zhu, Guoshi Wan, Enguo Chen, Riqing Chen, Chenhui Su, Hong Xu, Xiongjun Fu, Wenwen Kong, Jisong Zhang   +9 more
wiley   +1 more source

Overexpression of efflux pump and biofilm associated genes in itraconazole resistant Candida albicans isolates causing onychomycosis

Scientific Reports
Candida onychomycosis is a common fungal nail infection where treatment efficacy can be compromised by antifungal resistance. This study investigates the role of efflux pump genes (CDR1, CDR2, and MDR1) and biofilm-associated genes (ALS1, ALS3) in ...
Hasti Nouraei, Neda Amirzadeh, Hossein Khodadadi, Mehdi Ghahartars, Zahra Zareshahrabadi, Reza Nasr, Seyed Jamal Hashemi, Kambiz Diba, Kamiar Zomorodian, Keyvan Pakshir   +9 more
doaj   +1 more source

A Multifactorial Azole Response in Clinically Relevant Fusarium Species Complexes

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Background Fusarium spp. are clinically relevant filamentous fungi with intrinsically low susceptibility to multiple antifungal agents, particularly azoles, and are included in the World Health Organization fungal priority pathogens list.
Patrícia Helena Grizante Barião, Ludmilla Tonani, Adriana Rodrigues Alves, Otávio Guilherme Gonçalves de Almeida, Cledir Santos, Marcia Regina von Zeska Kress   +5 more
wiley   +1 more source