Results 211 to 220 of about 56,596 (269)

Establishment of epidemiological cutoff values against <i>Fonsecaea monophora</i>, an agent of chromoblastomycosis and cerebral phaeohyphomycosis. [PDF]

J Clin Microbiol
Smith DJ, van Beurden T, Li Y, Almeida-Paes R, Jacomel B, Vicente VA, Lustosa BPR, Walter TH, Neto ENM, Hallur V, Paul D, Paul N, Li R, Lu S, Kidd SE, Bonifaz A, Samaddar A, Treviño-Rangel RdJ, González GM, Chowdhary A, Brunellie JGP, García-Effron G, Rudramurthy SM, Kaur H, Chakrabarti A, de Azevedo CdMPeS, Marques SG, Santos DWCL, Cognialli RCR, Queiroz-Telles F, Spruijtenburg B, Meijer EFJ, de Groot T, Seyedmousavi A, Dufresne PJ, Lockhart SR, Wiederhold NP, Song Y, Hagen F.   +38 more
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A Retrospective, Comparative Cohort Analysis of the Utilization of Voriconazole-Containing Regimens Versus Itraconazole in the Treatment of Blastomycosis. [PDF]

J Fungi (Basel)
Schanz CC, Rivera CG, Saleh OMA, Clement J, Enzler MJ, Firkus D, Cole K, Vergidis P, Stevens RW.   +8 more
europepmc   +1 more source

A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia.

Blood
Himonas E, de Beauchamp L, Zerbst D, Desmares-Romain E, Sarnello D, Kalkman ER, Rattigan KM, James D, Shokry E, Copland M, Griessinger E, Récher C, De Mas V, Vergez F, Sumpton D, Schimmer AD, Minden MD, Gottlieb E, Shanks E, Sarry JE, Helgason GV.   +20 more
europepmc   +1 more source

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Efficacy of 12-months oral itraconazole versus 6-months oral itraconazole to prevent relapses of chronic pulmonary aspergillosis: an open-label, randomised controlled trial in India.

Lancet. Infectious Diseases (Print), 2022
BACKGROUND Chronic pulmonary aspergillosis has a 5-year mortality of 50-80% globally, and the optimal duration of treatment for chronic pulmonary aspergillosis remains unclear.
I. Sehgal, S. Dhooria, V. Muthu, K. Prasad, A. Aggarwal, A. Chakrabarti, Hansraj Choudhary, M. Garg, R. Agarwal   +8 more
semanticscholar   +1 more source

Thermosensitive and mucoadhesive in situ ocular gel for effective local delivery and antifungal activity of itraconazole nanocrystal in the treatment of fungal keratitis.

International journal of pharmaceutics, 2021
Itraconazole is a lipophilic drug, which limits its absorption for ocular administration. This study focused on the incorporation of itraconazole into nanocrystalline carrier system with stabilizer Pluronic® F127 and was further formulated into ...
Andi Dian Permana, Rifka Nurul Utami, Patricia Layadi, Achmad Himawan, Nana Juniarti, Qonita Kurnia Anjani, Emilia Utomo, Sandra Aulia Mardikasari, A. Arjuna, R. Donnelly   +9 more
semanticscholar   +1 more source

A randomised trial of prednisolone versus prednisolone and itraconazole in acute-stage allergic bronchopulmonary aspergillosis complicating asthma

European Respiratory Journal, 2021
Background Whether a combination of glucocorticoid and antifungal triazole is superior to glucocorticoid alone in reducing exacerbations in patients with allergic bronchopulmonary aspergillosis (ABPA) remains unknown. We aimed to compare the efficacy and
R. Agarwal, V. Muthu, I. Sehgal, S. Dhooria, K. Prasad, M. Garg, A. Aggarwal, A. Chakrabarti   +7 more
semanticscholar   +1 more source

Itraconazole

Expert Opinion on Pharmacotherapy, 2000
Itraconazole is a broad spectrum triazole antifungal agent. It has favourable pharmacodynamic and pharmacokinetic profiles and is available as both oral and i.v. formulations. Over the last two decades, clinical and animal infection studies have demonstrated the efficacy of itraconazole in a wide range of superficial fungal infections including ...
G E, Piérard, J E, Arrese, C, Piérard-Franchimont   +2 more
openaire   +2 more sources

Pharmacology of Itraconazole

Drugs, 2001
Itraconazole is a triazole antifungal agent that has a broad spectrum of activity and is well tolerated. Itraconazole is highly efficacious, particularly because its main metabolite, hydroxy-itraconazole, also has considerable antifungal activity. The original capsule formulation of itraconazole may lead to variability in absorption and the plasma ...
K, De Beule, J, Van Gestel
openaire   +2 more sources

Itraconazole attenuates the stemness of nasopharyngeal carcinoma cells via triggering ferroptosis

Environmental Toxicology, 2020
Radiotherapy is a common therapy method for nasopharyngeal carcinoma (NPC) treatment; however, radioresistance greatly limits the clinical efficiency and prognosis of NPC patients.
Ying Xu, Qian Wang, Xiaozhen Li, Yingyan Chen, Gang Xu   +4 more
semanticscholar   +1 more source

Intravenous Itraconazole

Annals of Pharmacotherapy, 2001
OBJECTIVE: To review the pharmacology, mycology, chemistry, pharmacokinetics, efficacy, safety, tolerability, dosage, administration, and economic issues of intravenous itraconazole. DATA SOURCES: A MEDLINE search from 1978 to June ...
D, Slain, P D, Rogers, J D, Cleary, S W, Chapman   +3 more
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