Comparative Analysis of Label-Free and 8-Plex iTRAQ Approach for Quantitative Tissue Proteomic Analysis. [PDF]
PLoS ONE, 2015 High resolution proteomics approaches have been successfully utilized for the comprehensive characterization of the cell proteome. However, in the case of quantitative proteomics an open question still remains, which quantification strategy is best ...
Agnieszka Latosinska +12 more
doaj +1 more source
Analysis of multidrug resistance in Streptococcus suis ATCC 700794 under tylosin stress
Virulence, 2019 Streptococcus suis is an important zoonotic pathogen. The massive use of tylosin and other antibiotics in swine production has led to the emergence of resistant phenotypes of S. suis.
Rui-Xiang Che +13 more
doaj +1 more source
Pb2+ tolerance by Frankia sp. strain EAN1pec involves surface-binding [PDF]
, 2017 Several Frankia strains have been shown to be lead-resistant. The mechanism of lead resistance was investigated for Frankia sp. strain EAN1pec. Analysis of the cultures by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDAX ...
Furnholm, Teal +3 more
core +2 more sources
Apex Peptide Elution Chain Selection: A New Strategy for Selecting Precursors in 2D-LC-MALDI-TOF/TOF Experiments on Complex Biological Samples [PDF]
, 2010 LC-MALDI provides an often overlooked opportunity to exploit the separation between LC-MS and MS/MS stages of a 2D-LC-MS-based proteomics experiment, that is, by making a smarter selection for precursor fragmentation. Apex Peptide Elution Chain Selection
Breitling, Rainer, +5 more
core +3 more sources
OCAP: an open comprehensive analysis pipeline for iTRAQ [PDF]
Bioinformatics, 2012 Abstract Motivation: Mass spectrometry-based iTRAQ protein quantification is a high-throughput assay for determining relative protein expressions and identifying disease biomarkers. Processing and analysis of these large and complex data involves a number of distinct components and it is desirable to have a pipeline to efficiently ...
Penghao, Wang +2 more
openaire +2 more sources
Proteomes, 2019 Two-dimensional gel electrophoresis (2DE) is an important and well-established technical platform enabling extensive top-down proteomic analysis. However, the long-held but now largely outdated conventional concepts of 2DE have clearly impacted its ...
Xianquan Zhan +5 more
doaj +1 more source
Integrative analysis of the colorectal cancer proteome : potential clinical impact [PDF]
, 2016 Peer ...
Alnabulsi, Abdo, Murray, Graeme I.
core +2 more sources
iTRAQ-based proteomic analysis of duck muscle related to lipid oxidation
Poultry Science, 2021 Lipid oxidation is the main cause of quality deterioration in meat and meat products. To facilitate the identification of candidate molecular biomarkers that are linked to lipid oxidation, we performed the proteomic analysis of duck muscle using isobaric
Muhan Zhang +4 more
doaj +1 more source
A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers [PDF]
, 2013 Novel anticancer drugs targeting key apoptosis regulators have been developed and are undergoing clinical trials. Pharmacodynamic biomarkers to define the optimum dose of drug that provokes tumor apoptosis are in demand; acquisition of longitudinal tumor
Brown, G. +14 more
core +3 more sources
Comparative proteomics analysis of two maize hybrids revealed drought-stress tolerance mechanisms
Biotechnology & Biotechnological Equipment, 2020 Drought is a major abiotic stress factor that affects the yield of maize (Zea mays L.) during the grain filling period. Therefore, it is critical to reveal the molecular mechanisms underlying maize drought stress tolerance. To analyze the characteristics
Anyi Dong +7 more
doaj +1 more source