Results 51 to 60 of about 17,544 (219)

DIGE and iTRAQ as biomarker discovery tools in aquatic toxicology [PDF]

Ecotoxicology and Environmental Safety, 2012
Molecular approaches in ecotoxicology have greatly enhanced mechanistic understanding of the impact of aquatic pollutants in organisms. These methods have included high throughput Omics technologies, including quantitative proteomics methods such as 2D differential in-gel electrophoresis (DIGE) and isobaric tagging for relative and absolute ...
Christopher J, Martyniuk, Sophie, Alvarez, Nancy D, Denslow   +2 more
openaire   +2 more sources

Majorbio Cloud 2026 Update: An End‐to‐End Solution for Proteomics Research

iMetaMed, EarlyView.
The recent upgrade of Majorbio Cloud facilitates a more streamlined and accurate research process, aiding researchers across the various proteomics subfields. Furthermore, it propels the advancement of multi‐layered, multi‐omics scientific investigations centered around proteins.
Caiping Shi, Chang Han, Jichen Han, Bing Yang, Yachen Dong, Jianhua Zhao, Binxu Liu, Rundong Fang, Wenyao Fu, Jiawen Ma, Meng Luo, Lixing Feng, Yitong Feng, Huimin Cui, Mengxi Li, Huasheng Huang, Xianglin Zhang, Kegang Yu   +17 more
wiley   +1 more source

ITRAQ-Based Proteomic Analysis of the Metabolic Mechanisms Behind Lipid Accumulation and Degradation during Peanut Seed Development and Postgermination

, 2016
Peanut seeds have a high oil content making them an important oil crop. During development and germination, seeds undergo complex dynamic and physiological changes.
Dongmei Yin (370645), Xingguo Zhang (456808), Dangqun Cui (479000), Xiaoyan He (417003), Xingli Ma (3228093), Hemin Li (456809), Yun Wang (32846)   +6 more
core   +1 more source

Quantitative proteomics analysis of proteins involved in alkane uptake comparing the profiling of Pseudomonas aeruginosa SJTD-1 in response to n-octadecane and n-hexadecane. [PDF]

PLoS ONE, 2017
While many data are available on genes encoding proteins for degradation of hydrocarbons in bacteria, the impact of alkane on transporter protein expression is unclear.
Xuefeng Zhou, Xuejiao Xing, Jingli Hou, Jianhua Liu   +3 more
doaj   +1 more source

Isobaric tags for relative and absolute quantitation in identifying proteins for clozapine treatment response in patients with schizophrenia: A preliminary study

Taiwanese Journal of Psychiatry, 2021
Objective: Schizophrenia is a mental disorder characterized by reduced social engagement, abnormal emotional expression, and a lack of motivation. Isobaric tags for relative and absolute quantitation (iTRAQ) are a novel proteomic technique. In this study,
Chin- Chuen Lin, Hung Su, Jentaie Shiea, Tiao- Lai Huang   +3 more
doaj   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

A Proteomic Analysis of the Malignant Mesothelioma Secretome Using iTRAQ [PDF]

Cancer Genomics & Proteomics, 2017
Backgound/Aim: Malignant mesothelioma (MM) is an aggressive and fatal pleural cancer. The cell secretome offers information allowing insight into the pathogenesis of MM while offering the possibility to identify potential therapeutic targets and biomarkers.
Jenette, Creaney, Ian M, Dick, Justine S, Leon, Bruce W S, Robinson   +3 more
openaire   +2 more sources

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Quantitative proteomic analysis of upland cotton stem terminal buds reveals phytohormone-related pathways associated with dwarfism

Biologia Plantarum, 2017
Identifying important regulative elements and pathways related to dwarfism in cotton is a major challenge in cotton breeding. Isobaric tags for relative and absolute quantitation-based proteomics of stem terminal buds from upland cotton (Gossypium ...
X. Tu, J. Li, Q. Wang, A. Liu
doaj   +1 more source

Screening of Differential Expression Proteins in Rat Brain Tissues after DAI by iTRAQ-LC-MS/MS [PDF]

Fayixue Zazhi, 2017
Objective To screen for the differential expression proteins in brain tissues of SD rat after diffuse axonal injury （DAI） by isobaric tag for relative and absolute quantification-liquid chromatograph-mass spectrometer/mass spectrometer （iTRAQ-LC-MS/MS ...
CHEN QING, BAI JIE, ZHANG WEN-FANG
doaj   +1 more source