Results 71 to 80 of about 17,544 (219)
Two-dimensional gel electrophoresis (2DE) is an important and well-established technical platform enabling extensive top-down proteomic analysis. However, the long-held but now largely outdated conventional concepts of 2DE have clearly impacted its ...
Xianquan Zhan +5 more
doaj +1 more source
Non-Hodgkin’s lymphoma (NHL) is the third most common malignant tumor among children. However, at initial NHL diagnosis, most cases are at an advanced stage because of nonspecific clinical manifestations and currently limited diagnostic methods.
Runhong Yu +9 more
doaj +1 more source
Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
Sex‐stratified analyses of the TCGA and CGGA cohorts have identified promoter‐proximal TACSTD2 CpG sites where methylation shows opposite survival associations in males and females, is independent of copy number, and correlates with TACSTD2 expression.
Tahreem Fatima
wiley +1 more source
iTRAQ, a New Prospect of Toxicogenomics
Toxicogenomics is a high throughput molecular profiling technologies, it is the study of the structure and function of the genome as it responds to adverse xenobiotic exposure.
openaire +1 more source
Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)
Ceramides play a crucial role in divergent signaling events, including differentiation, senescence, proliferation, and apoptosis. Ceramides are a minor lipid component in terms of content; thus, highly sensitive detection is required for accurate ...
Takuji Nabetani +8 more
doaj +1 more source
Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm
Pyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Katie C. Sprinkel +2 more
wiley +1 more source
iTRAQ Analysis with Paul Ion Trap–Obstacle Solved [PDF]
Mass spectrometers equipped with ion trap analyzers have been significantly improved due to their high performance and wide application area accompanying the low costs of purchase. Despite several advantages, such as reasonable resolution at low cost, high sensitivity, and capability for multistage analysis, ion traps have an important drawback: low ...
Anna, Drabik +4 more
openaire +2 more sources
iTRAQ data of murin melanoma tissue sample
iTRAQ data of the B16F10 murine melanoma tissue sample form the in vivo study of a highly concentrated form of fermented wheat germ ...
Bencze, G (via Mendeley Data)
core +2 more sources
Peng Chen,1 Dongsheng Lin,2 Chen Wang,2 Cuiwen Song,1 Wenjing Wang,1 Jinglian Qu,1 Zhibing Wu2 1Basic Medical School, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, People’s Republic of China; 2First Clinical Medical School ...
Chen P +6 more
doaj

