Results 51 to 60 of about 25,211 (209)
Objective: Schizophrenia is a mental disorder characterized by reduced social engagement, abnormal emotional expression, and a lack of motivation. Isobaric tags for relative and absolute quantitation (iTRAQ) are a novel proteomic technique. In this study,
Chin- Chuen Lin +3 more
doaj +1 more source
Pyridoxal (PL) exhibits the strongest anti‐tumor activity within the vitamin B6 family, demonstrating significant ovarian cancer cell‐killing efficacy in vivo, in vitro, and in patient‐derived organoid (PDO) models. The anti‐tumor mechanism involves PL inducing a shift in peroxisome dynamics towards fission, promoting peroxisome proliferation, and ...
Ruonan Li +12 more
wiley +1 more source
iTRAQ-based proteomics reveals novel biomarkers of osteoarthritis [PDF]
We performed comprehensive proteomic analyses of articular cartilage by using the isobaric tags for relative and absolute quantitation (iTRAQ) method, and searched for candidate biomarkers for osteoarthritis (OA).Articular cartilage was collected from patients with OA or femoral neck fracture for the control group. Molecular variations were detected by
Ikeda, Daiki +3 more
openaire +2 more sources
Peng Chen,1 Dongsheng Lin,2 Chen Wang,2 Cuiwen Song,1 Wenjing Wang,1 Jinglian Qu,1 Zhibing Wu2 1Basic Medical School, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, People’s Republic of China; 2First Clinical Medical School ...
Chen P +6 more
doaj
Quantitative proteomics analysis of proteins involved in alkane uptake comparing the profiling of Pseudomonas aeruginosa SJTD-1 in response to n-octadecane and n-hexadecane. [PDF]
While many data are available on genes encoding proteins for degradation of hydrocarbons in bacteria, the impact of alkane on transporter protein expression is unclear.
Xuefeng Zhou +3 more
doaj +1 more source
Evolutionary descent of prion genes from a ZIP metal ion transport ancestor [PDF]
In the more than 20 years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP) have remained enigmatic.
David Westaway +4 more
core +1 more source
Protein Profiling of Arabidopsis Roots Treated With Humic Substances: Insights Into the Metabolic and Interactome Networks [PDF]
Background and Aim: Humic substances (HSs) influence the chemical and physical properties of the soil, and are also known to affect plant physiology and nutrient uptake.
Antonio Masi +9 more
core +4 more sources
Lymph‐based liquid biopsy: Current progress and future potential
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu +6 more
wiley +1 more source
Screening of serum biomarkers of preeclampsia by proteomics combination with bioinformatics
Objective: To screen for novel predictive serum markers of preeclampsia (PE). Method: Blood samples were collected from seven women with PE and five with healthy pregnancies.
Yuee Ling, Jie Su, Jie Lin, Sumei Wang
doaj +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source

