Results 161 to 170 of about 34,014 (241)

Association of Variability of Monthly Continuous Glucose Monitoring‐Derived Metrics With Diabetic Kidney Disease in Type 1 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background While HbA1c is the standard for monitoring long‐term glycaemic control, it fails to capture glycaemic variability. We investigated the discriminatory capacity of longitudinal continuous glucose monitoring (CGM) metrics and identified CGM metric patterns associated with diabetic kidney disease (DKD) in individuals with type 1 ...
Byeongjae Kang, Rosa Oh, Taeyoung Kim, Jee Hee Yoo, Danbee Kang, Gyuri Kim, Sang‐Man Jin, Myung Jin Chung, Jae Hyeon Kim   +8 more
wiley   +1 more source

Combination treatment with synthetic gRNA/Cas12a and gRNA/Cas9 ribonucleoproteins disrupts HIV replication and expression. [PDF]

iScience
Banik P, Wang L, Schank M, Pyburn JS, Hill AC, Zhang Y, Zhao J, Orfield HK, Leshaodo TO, Lightner JW, Wu XY, Ning S, El Gazzar M, Moorman JP, Yao ZQ.   +14 more
europepmc   +1 more source

How Regulatory Costs Impede Financial Technology Gains

European Financial Management, EarlyView.
ABSTRACT While financial technology innovation lowers intermediation costs, regulatory frictions may prevent these gains from reaching long‐term investors and borrowers. Using variation in retail investor participation driven by state securities registration lapses in peer‐to‐peer lending, we demonstrate that regulatory frictions are associated with ...
Shyam Venkatesan, Brian Wolfe, Woongsun Yoo   +2 more
wiley   +1 more source

Evidence-Based Guidelines for the Diagnosis and Treatment of Pediatric CKD-Mineral and Bone Disorder (Version 2024). [PDF]

Kidney Int Rep
Wang M, Xiong HY, Zhu C, Yu X, Jiao J, Tan L, Shen Y, Xu H, Mao J, Zhou J, Jiang XY, Shen Q, Wang F, Huang S, Huang W, Xia ZK, Liu XR, Wang H, Wu YB, Yu L, Tao YH, Gao CL, Li YJ, Sun SZ, Zhang DF, Shao XS, Zhao LJ, Wang X, Dang XQ, Huang HM, Chen Y, Li Q, Zhang AH, Subspecialty Group of Nephrology, the Society of Pediatrics, Chinese Medical Association.   +35 more
europepmc   +1 more source

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

The FEBS Journal, EarlyView.
Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo, Virginia Jiang, Philip D. Jeffrey, Angela Zhu, A. James Link, Jerelle A. Joseph, Jonathan M. Conway   +6 more
wiley   +1 more source

Human leukocyte antigen-G in solid tumors: from immunotolerance to immunotherapy. [PDF]

Front Immunol
Lin A, Yan WH.
europepmc   +1 more source

Site Fidelity, Depth Preference and Vertical Movement Patterns of Lentic and Lotic European Catfish Silurus glanis

Fisheries Management and Ecology, EarlyView.
ABSTRACT To study variables that may trigger the dispersion of the currently expanding European catfish in its native distribution limits, 42 individuals were captured from Upper Lake Constance (lentic) and 42 from two streaming tributaries (lotic), fitted with pressure and temperature loggers, and released at the site of capture (control: lotic or ...
Albert Ros, Jan Baer, Matthias Fromherz, Juergen Geist, Alexander Brinker   +4 more
wiley   +1 more source

Discovery of two novel mutations, R52H and N868D, in the voltage-gated sodium channel of Aedes aegypti associated with pyrethroid resistance. [PDF]

PLoS Negl Trop Dis
Chung HH, Teng HJ, Chen SL.
europepmc   +1 more source

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source

Therapeutic Potential of Vanillylacetone in Ameliorating CCl4-Induced Cardiotoxicity by targeting TNF-α/ NF-κB/TGF-β1 Pathways: Evidence from Biochemical, Histopathological, and Computational Analyses. [PDF]

ACS Omega
Alam MF, Altowairqi NAS, Mawkili W, Shoaib A, Fatima JE, Dallak MA, Abu Rabtah DAI, Hazazi AMA, Jali AM, Anwer T, Qadri M, Al-Masrahi MY, Alarifi A.   +12 more
europepmc   +1 more source