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Reaching Elimination of Onchocerciasis Transmission with Long-term Vector Control and Ivermectin Treatment in West Africa: The Example of Togo

open access: yes
Basanez M   +11 more
europepmc   +1 more source

Pharmacology of ivermectin [PDF]

open access: possibleParasitology Today, 1988
Ivermectin is a semi-synthetic macrocyclic lactone (Fig. I) active in single low doses against many parasites - particularly nematodes and arthropods. It has been registered for animal health use since early 1985, and was earlier this year approved for human use by the French Directorate o f Pharmacy and Drugs.
James L. Bennett, J.F. Williams, V. Dave
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Ivermectin

Dermatologic Clinics, 2003
Ivermectin is a potent antiparasitic drug and the first commercially available member of a new class of drugs (macrocyclic lactones) that has been approved for human use. Ivermectin has already proven to be highly effective in the elimination of river blindness as a public health burden.
George W, Elgart, Terri L, Meinking
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Ivermectin and filariasis

Fundamental & Clinical Pharmacology, 2003
AbstractIvermectin, a parasiticide that long ago proved its worth in veterinary medicine, became one of the most effective tools for control programs against human filarial diseases in the 1980s. It is provided at no cost, is effective against microfilariae (blocking their transmission) and can be administered annually as a single oral dose with ...
P. Gaxotte   +2 more
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Ivermectine

Annales de Dermatologie et de Vénéréologie, 2004
Ivermectin is a semi-synthetic derivative of a macrocyclic lactone. It causes paralysis in many nematodes and arthropodes because of its effect on ion-channels in cell membranes. Ivermectin was first used in veterinary medicine. In man, it was shown to be microfilaricid against Onchocerca volvulus. Most of the adverse reactions following treatment were
openaire   +2 more sources

The discovery of ivermectin

Trends in Parasitology, 2015
In September, Trends in Parasitology published two articles related to the discovery of ivermectin and the acknowledgement of Dr Satoshi Omura receiving the 2014 Gairdner Global Health Award for his contribution. Although Dr Omura isolated the avermectin-producing microorganism Streptomyces avermitilis, many other scientists and researchers contributed
Hugh R. Taylor, David H. Molyneux
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Ivermectin in scabies

Current Opinion in Infectious Diseases, 2002
The standard treatment for scabies has long been based on topical scabicides. Ivermectin, a broad-spectrum anti-parasitic agent, was first used in veterinary medicine. This drug, active against nematodes and arthropods, is used in humans for the treatment of filariasis.
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Ivermectin: An update

Parasitology Today, 1985
Ivermecan was introduced as an antiparasitic agent in 1981. It is now registered for animal-health use in 35 countries and is being evaluated for possible use in man. This review summarises its antiparasitic efficacy and apparent mode of action. Additional information is given in previous review articles.
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