Results 111 to 120 of about 22,962,330 (351)

Численное моделирование роста радиальной трещины в стальном кольцевом образце [PDF]

open access: yes, 2009
При чисельному моделюванні росту тріщини в зразках запропонований двох параметричний критерій нестабільного росту тріщини, який включає J-інтеграл та кут розкриття тріщини.At numerical modeling of growth of a crack the two-parametrical criterion of as ...
Маковей, В. А.   +1 more
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Effect of hold time on creep-fatigue crack propagation in lead-free solder

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Crack propagation tests of lead-free solder were conducted using center-notched plates under load- and displacement-controlled conditions of cyclic tension-compression. Four waveforms were adopted for tests: pp waveform having fast loading and unloading,
Keisuke TANAKA   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An Experimental Study on Rate Sensitivity of J-Integral and its Evaluation by Small Punch Test for TRIP Steel

open access: yesEngineering Transactions, 2014
Recently, much attention has been paid to TRIP steel since it indicates both high ductility and strength by strain induced martensitic transformation. This transformation allows TRIP steel to offer larger energy absorption than other steel at the same ...
Leishi SHI   +2 more
doaj   +1 more source

ZIP3D: An elastic and elastic-plastic finite-element analysis program for cracked bodies [PDF]

open access: yes
ZIP3D is an elastic and an elastic-plastic finite element program to analyze cracks in three dimensional solids. The program may also be used to analyze uncracked bodies or multi-body problems involving contacting surfaces.
Newman, J. C., Jr., Shivakumar, K. N.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

R curve obtained by a round bar with a circumferential crack and its effectiveness for a fracture toughness test (For a material with medium fracture toughness)

open access: yesNihon Kikai Gakkai ronbunshu
A non-standard circumferentially cracked round bar (CRB) specimen has been examined for replacement of the standard fracture toughness CT specimen since 1981.
Koichi KASABA   +2 more
doaj   +1 more source

Translational and extensional energy release rates (the J- and M-integrals) for a crack layer in thermoelasticity [PDF]

open access: yes
A number of papers have been presented on the evaluation of energy release rate for thermoelasticity and corresponding J integral. Two main approaches were developed to treat energy release rate in elasticity.
Chudnovsky, A., Gommerstadt, B.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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