Results 131 to 140 of about 22,686,556 (351)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Modelling the double cantilever beam test with bending moments by using bilinear discontinuous cohesive laws [PDF]
, 2015 A theoretical model of the double cantilever beam tests with bending moments (DCB-UBM) is presented. The specimen is modelled as the assemblage of two laminated beams connected by a cohesive interface.
Sørensen, Bent F. +2 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Calculation and Analysis of Crack Stress Intensity Factor and
Jixie chuandong, 2020 The distribution of stress intensity factor and J integral of helical gear with three-dimensional crack under different initial crack parameters is studied. The finite element software is used to analyze the helical gear with initial crack.
Guangyao Sun +2 more
doaj
Rationale methodologies calculating J-integral for through-wall cracked pipes load by combination force, bending moment and pressure. Part:ІІ [PDF]
, 2012 Розглянуто граничні стани труб із наскрізною коловою тріщиною різних розмірів та співвідношень середнього радіуса до товщини її стінки при дії комбінованого навантаження тиском, силою та поперечним моментом,що відповідає практичним потребам підприємств ...
Kryshchuk, M. +3 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Численное моделирование роста радиальной трещины в стальном кольцевом образце [PDF]
, 2009 При чисельному моделюванні росту тріщини в зразках запропонований двох параметричний критерій нестабільного росту тріщини, який включає J-інтеграл та кут розкриття тріщини.At numerical modeling of growth of a crack the two-parametrical criterion of as ...
Маковей, В. А. +1 more
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
ZIP3D: An elastic and elastic-plastic finite-element analysis program for cracked bodies [PDF]
ZIP3D is an elastic and an elastic-plastic finite element program to analyze cracks in three dimensional solids. The program may also be used to analyze uncracked bodies or multi-body problems involving contacting surfaces.
Newman, J. C., Jr., Shivakumar, K. N.
core +1 more source