Investigation of crack propagation in single optical fiber composite with thermal influence by finite element method [PDF]
, 2010 Two parallel comparative ‘Conventional Method and Computer Simulation using ANSYS software’ for prediction of crack growth and its behavior in optical fiber are studied and presented in this work.
Ahanchian Mohammad +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Analysis of some localized boundary-domain integral equations [PDF]
, 2009 Some direct segregated localized boundary-domain integral equation (LBDIE) systems associated with the Dirichlet and Neumann boundary value problems (BVP) for a scalar "Laplace" PDE with variable coefficient are formulated and analysed. The parametrix is
Chkadua, O +2 more
core +1 more source
Experimental investigation on possible dependence of plastic zone size on specimen geometry [PDF]
In this investigation the extent of the plastic zone size ahead of a crack-tip in single edge notched tension (SENT), compact tension (CT) specimens has been examined experimentally by micro-hardness technique and by elastic-plastic finite element ...
Kudari, S. K., Maiti, B., Ray, K. K.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Journal of Stroke and Cerebrovascular DiseasesBackground: The Buenos Aires Stroke School was established in 2019 to address the unmet need for structured, high-quality stroke education in Latin America.
Matías J. Alet +2 more
doaj +1 more source
Implementation of equivalent domain integral method in the two-dimensional analysis of mixed mode problems [PDF]
An equivalent domain integral (EDI) method for calculating J-intergrals for two-dimensional cracked elastic bodies is presented. The details of the method and its implementation are presented for isoparametric elements.
Raju, I. S., Shivakumar, K. N.
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Double noding technique for mixed mode crack propagation studies [PDF]
A simple dynamic finite element algorithm for analyzing a propagating mixed mode crack tip is presented. A double noding technique, which can be easily incorporated into existing dynamic finite element codes, is used together with a corrected J integral ...
Emergy, A. F. +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source