Results 111 to 120 of about 19,209,998 (295)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Modelling granular soil to predict pressures on integral bridge abutments
Presented here is a granular soil model created to investigate the soil pressureswhich develop behind integral bridge abutments. The problem is introduced along with a briefsummary of the fundamental behaviour, the model produced, and the initial ...
Banks, J.R +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Integral Trees with Spectral Radius 3 [PDF]
There are eleven integral trees with largest eigenvalue 3.Integral graphs;graph spectra ...
Brouwer, A.E., Haemers, W.H.
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Catalogue of maximum crack opening stress for CC(T) specimen assuming large strain condition
Open Engineering, 2013 Graba Marcin
doaj +1 more source
A J-INTEGRAL MEASUREMENT METHOD BASED ON DIGITAL IMAGE CORRELATION
Jixie qiangdu, 2018 J-integral is an important fracture parameter which quantitatively describes the stress and strain fields near a crack tip. Accurate and efficient measurement of J-integral is of great significance for the evaluation of crack stability and propagation in
JIANG Wei, JIANG XianFeng, HUANG YuLong
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
A Simple Method for Estimation of J-Integral and Modified J-Integral
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1981 Kiyotsugu OHJI, Keiji OGURA, Shiro KUBO
openaire +2 more sources