Results 141 to 150 of about 22,962,330 (351)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Catalogue of maximum crack opening stress for CC(T) specimen assuming large strain condition
Open Engineering, 2013 Graba Marcin
doaj +1 more source
A J-INTEGRAL MEASUREMENT METHOD BASED ON DIGITAL IMAGE CORRELATION
Jixie qiangdu, 2018 J-integral is an important fracture parameter which quantitatively describes the stress and strain fields near a crack tip. Accurate and efficient measurement of J-integral is of great significance for the evaluation of crack stability and propagation in
JIANG Wei, JIANG XianFeng, HUANG YuLong
doaj
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Simple Method for Estimation of J-Integral and Modified J-Integral
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1981 Kiyotsugu OHJI, Keiji OGURA, Shiro KUBO
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Research on J integral of Crack Tip on Intersecting Line of Fracturing Pump Head
Shiyou jixie, 2018 To address the primary failure modes of the fracturing pump head, a finite element model with different angular crack size is established. The J integral of the crack front and the plastic zone size of the crack tip are calculated.
Wei Chao, Zhou Sizhu, Hua Jian, Zhang Si
doaj
Hydrogen Embrittlement Evaluation of Micro Alloyed Steels by Means of J-Integral Curve. [PDF]
Materials (Basel), 2019 Cabrini M +5 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source