Results 51 to 60 of about 22,962,330 (351)

On the exceptional damage-tolerance of gradient metallic materials [PDF]

open access: yes, 2020
An experimental study is described on the fracture toughness and micro-mechanisms associated with the initiation and propagation of cracks in metallic nickel containing marked gradients in grain size, ranging from ∼30 nm to ∼4 μm.
Cao, R   +6 more
core  

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers   +5 more
wiley   +1 more source

Nonlinear Fatigue Crack Growth Simulations using J-integral Decomposition and XFEM

open access: yes, 2017
In the present work, nonlinear fatigue crack growth analysis of an inclined edge crack is performed by extended finite element method (XFEM) [1] . The material behavior is assumed to be nonlinear, which is modelled by Ramberg-Osgood model and von-Mises ...
Manish Kumar   +6 more
semanticscholar   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell   +3 more
wiley   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Mode I crack tip fields: strain gradient plasticity theory versus J2 flow theory

open access: yes, 2019
The mode I crack tip asymptotic response of a solid characterised by strain gradient plasticity is investigated. It is found that elastic strains dominate plastic strains near the crack tip, and thus the Cauchy stress and the strain state are given ...
Fleck, Norman A.   +1 more
core   +1 more source

Exact results with the J-integral applied to free-boundary flows [PDF]

open access: yes, 2002
We apply the J-integral to free-boundary flows in a channel geometry such as viscous fingering or blob injection in Hele-Shaw cells, void propagation in electromigration, and injection of air bubbles into inviscid liquids.
Ben Amar, Martine, Rice, James R.
core   +1 more source

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt   +76 more
wiley   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Crack Propagation under Rolling Contact Fatigue near the White Etching Layer of a Railway Wheel

open access: yesTribology Online
A railway wheel flat occurs when the wheel locks and slides along the rail, forming a white etching layer (WEL) just under the flat surface where rolling contact fatigue cracks often form that can propagate into the wheel and spall during service.
Wijitpatima Chawanat, Makoto Akama
doaj   +1 more source

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