Results 61 to 70 of about 19,209,998 (295)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

EXPERIMENTAL STUDY ON J-INTEGRAL VALUE FOR THREE-POINT BEND SPECIMEN

open access: yesJixie qiangdu, 2017
Using two different kinds of three-point bend specimens,J-integral values calculated based on plastic area of under load-notch-opening displacement curve, according to GB/T 21143-2014 and GB/T 21143-2007, GB/T 2358-1994 appendix D two standards,combining
SU HongYing   +4 more
doaj  

Benchmark analyses of probabilistic fracture mechanics for cast stainless steel pipe

open access: yesMechanical Engineering Journal, 2016
Performance demonstration certification of non-destructive inspection for cast stainless steel (CASS) has been planned but the target flaw depth to be detected has not been determined yet in Japan.
Kiminobu HOJO   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Numerical Analysis of the Influence of In-Plane Constraints on the Crack Tip Opening Displacement for SEN(B) Specimens Under Predominantly Plane Strain Conditions

open access: yesInternational Journal of Applied Mechanics and Engineering, 2016
This paper presents a numerical analysis of the relationship between in-plane constraints and the crack tip opening displacement (CTOD) for single-edge notched bend (SEN(B)) specimens under predominantly plane strain conditions.
M. Graba
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Positive solutions of a boundary value problem with integral boundary conditions [PDF]

open access: yes, 2011
We consider boundary-value problems studied in a recent paper. We show that some existing theory developed by Webb and Infante applies to this problem and we use the known theory to show how to find improved estimates on parameters μ*, λ so ...
Webb, J.
core   +4 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Analysis of segregated boundary-domain integral equations for mixed variable-coefficient BVPs in exterior domains [PDF]

open access: yes, 2011
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 Birkhäuser Boston.Some direct segregated systems of boundary–domain integral equations (LBDIEs) associated with the mixed
Mikhailov, SE   +5 more
core   +1 more source

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