Results 81 to 90 of about 22,686,556 (351)

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

IMPACT OF HARDENING ON J INTEGRAL AT THE SLIGHTLY CURVED ELASTICITY-PLASTICITY CRACK TIP UNDER QUASI-STATIC LOADS

open access: yesJixie qiangdu, 2016
J integral of elastic-plastic curved crack in hardened material under quasi-static loads has been mainly studied,and curved crack tip J integral has been calculated as a practical application of a second order perturbation method and theorem of surname ...
YANG DaPeng   +3 more
doaj  

Benchmark analyses of probabilistic fracture mechanics for cast stainless steel pipe

open access: yesMechanical Engineering Journal, 2016
Performance demonstration certification of non-destructive inspection for cast stainless steel (CASS) has been planned but the target flaw depth to be detected has not been determined yet in Japan.
Kiminobu HOJO   +9 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

EXPERIMENTAL STUDY ON J-INTEGRAL VALUE FOR THREE-POINT BEND SPECIMEN

open access: yesJixie qiangdu, 2017
Using two different kinds of three-point bend specimens,J-integral values calculated based on plastic area of under load-notch-opening displacement curve, according to GB/T 21143-2014 and GB/T 21143-2007, GB/T 2358-1994 appendix D two standards,combining
SU HongYing   +4 more
doaj  

Numerical Analysis of the Influence of In-Plane Constraints on the Crack Tip Opening Displacement for SEN(B) Specimens Under Predominantly Plane Strain Conditions

open access: yesInternational Journal of Applied Mechanics and Engineering, 2016
This paper presents a numerical analysis of the relationship between in-plane constraints and the crack tip opening displacement (CTOD) for single-edge notched bend (SEN(B)) specimens under predominantly plane strain conditions.
M. Graba
doaj   +1 more source

Obtaining the J-integral by diffraction-based crack-field strain mapping

open access: yes, 2016
The analysis by diffraction of polycrystalline materials can determine the full tensor of the elastic strains within them. Point-by-point maps of elastic strain can thus be obtained in fine-grained engineering alloys, typically using synchrotron X-rays ...
S. Barhli   +6 more
semanticscholar   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

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