Results 71 to 80 of about 19,209,998 (295)

Prediction of fully plastic J-integral for weld centerline surface crack considering strength mismatch based on 3D finite element analyses and artificial neural network

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2020
This work mainly focuses on determination of the fully plastic J-integral solutions for welded center cracked plates subjected to remote tension loading. Detailed three-dimensional elastic–plastic Finite Element Analyses (FEA) were implemented to compute
Chuanjie Duan, Shuhua Zhang
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Interfacial elastic J  integral for indentation test

open access: yesMechanical Engineering Journal, 2018
Recently, the indentation test has drawn attention as a new method for evaluating the interfacial fracture toughness, since its application enables the in-situ measurement using a Vickers hardness tester.
Masayuki ARAI
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The study of redistribution in residual stresses during fatigue crack growth

open access: yesJournal of Mechanical Engineering and Sciences, 2021
Numerical and experimental study was conducted on fatigue crack growth (FCG) of metallic components to investigate the redistribution of mechanical residual stresses during FCG.
M. Noghabi   +2 more
doaj  

Marine Shaft Steels (AISI 4140 and AISI 5120) Predicted Fracture Toughness by FE Simulation

open access: yesMedžiagotyra, 2017
Optimal selection of material can be considered as one of the most critical steps in engineering design process. That is especially emphasized when dealing with constructions that operate in marine environment; high stresses and harsh operating ...
Goran VUKELIC, Josip BRNIC
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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