Results 71 to 80 of about 22,962,330 (351)

EXPERIMENTAL STUDY ON J-INTEGRAL VALUE FOR THREE-POINT BEND SPECIMEN

open access: yesJixie qiangdu, 2017
Using two different kinds of three-point bend specimens,J-integral values calculated based on plastic area of under load-notch-opening displacement curve, according to GB/T 21143-2014 and GB/T 21143-2007, GB/T 2358-1994 appendix D two standards,combining
SU HongYing   +4 more
doaj  

Benchmark analyses of probabilistic fracture mechanics for cast stainless steel pipe

open access: yesMechanical Engineering Journal, 2016
Performance demonstration certification of non-destructive inspection for cast stainless steel (CASS) has been planned but the target flaw depth to be detected has not been determined yet in Japan.
Kiminobu HOJO   +9 more
doaj   +1 more source

Failure mode of laser welds in lap‐shear specimens of high strength low alloy (HSLA) steel sheets [PDF]

open access: yes, 2012
In this paper, the failure mode of laser welds in lap‐shear specimens of non‐galvanized SAE J2340 300Y high strength low alloy steel sheets under quasi‐static loading conditions is examined based on experimental observations and finite element analyses ...
Anand   +18 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Numerical Analysis of the Influence of In-Plane Constraints on the Crack Tip Opening Displacement for SEN(B) Specimens Under Predominantly Plane Strain Conditions

open access: yesInternational Journal of Applied Mechanics and Engineering, 2016
This paper presents a numerical analysis of the relationship between in-plane constraints and the crack tip opening displacement (CTOD) for single-edge notched bend (SEN(B)) specimens under predominantly plane strain conditions.
M. Graba
doaj   +1 more source

Obtaining the J-integral by diffraction-based crack-field strain mapping

open access: yes, 2016
The analysis by diffraction of polycrystalline materials can determine the full tensor of the elastic strains within them. Point-by-point maps of elastic strain can thus be obtained in fine-grained engineering alloys, typically using synchrotron X-rays ...
S. Barhli   +6 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A simulation method for fatigue-driven delamination in layered structures involving non-negligible fracture process zones and arbitrarily shaped crack fronts

open access: yes, 2019
Most of the existing methods for fatigue-driven delamination are limited to two-dimensional (2D) applications or their predictive capabilities have not been validated in three-dimensional (3D) problems.
Bak, Brian L. V.   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Prediction of fully plastic J-integral for weld centerline surface crack considering strength mismatch based on 3D finite element analyses and artificial neural network

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2020
This work mainly focuses on determination of the fully plastic J-integral solutions for welded center cracked plates subjected to remote tension loading. Detailed three-dimensional elastic–plastic Finite Element Analyses (FEA) were implemented to compute
Chuanjie Duan, Shuhua Zhang
doaj   +1 more source

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