Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
An equivalent domain integral method for three-dimensional mixed-mode fracture problems [PDF]
A general formulation of the equivalent domain integral (EDI) method for mixed mode fracture problems in cracked solids is presented. The method is discussed in the context of a 3-D finite element analysis.
Raju, I. S., Shivakumar, K. N.
core +1 more source
Tensile and Fracture Mechanical Properties of Styrene-Butadiene Rubbers (SBR) Filled with Industrial and Pyrolytic Carbon Blacks, and Organoclay [PDF]
In this work we examined effects of filler combinations (industrial carbon black (CB), pelletized pyrolytic carbon black (pCBp) and organoclay (I30.P) on the tensile mechanical and fracture mechanical properties of SBR rubbers.
Berki, Péter, Karger-Kocsis, József
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Interfacial elastic J integral for indentation test
Recently, the indentation test has drawn attention as a new method for evaluating the interfacial fracture toughness, since its application enables the in-situ measurement using a Vickers hardness tester.
Masayuki ARAI
doaj +1 more source
Antiplane-inplane shear mode delamination between two second-order shear deformable composite plates [PDF]
The second-order laminated plate theory is utilized in this work to analyze orthotropic composite plates with asymmetric delamination. First, a displacement field satisfying the system of exact kinematic conditions is presented by developing a double ...
Szekrényes, András
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Application of the J-Integral and Digital Image Correlation (DIC) to Determination of Multiple Crack Propagation Law of UHPC under Flexural Cyclic Loading. [PDF]
Niu Y +5 more
europepmc +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Correlation between the pivot node concept and fatigue crack closure [PDF]
The study of fatigue crack growth has been commonly done by means of bi-dimensional models and assuming a homogeneous behaviour through the thickness. According to the specimen thickness, a state of plane stress or plane strain is presumed.
Camas, Daniel +2 more
core

