Results 81 to 90 of about 22,962,330 (351)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Interfacial elastic J  integral for indentation test

open access: yesMechanical Engineering Journal, 2018
Recently, the indentation test has drawn attention as a new method for evaluating the interfacial fracture toughness, since its application enables the in-situ measurement using a Vickers hardness tester.
Masayuki ARAI
doaj   +1 more source

Evaluation of J-integral estimation procedures.

open access: yesJournal of the Society of Materials Science, Japan, 1987
The path independency of J-integral proposed by Rice has been accepted to be valid in both linear and nonlinear elastic materials. This independency, however, has not been necessarily proven for incremental elasto-plastic materials.In this paper, at first, FEM analyses based on deformation and incremental plasticity theories were performed in order to ...
Kenji HAYASHI   +2 more
openaire   +2 more sources

Subideals of operators II

open access: yes, 2012
A subideal (also called a J-ideal) is an ideal of a B(H)-ideal J. This paper is the sequel to Subideals of operators where a complete characterization of principal and then finitely generated J-ideals were obtained by first generalizing the 1983 work of ...
Patnaik, S., Weiss, G.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Tensile and Fracture Mechanical Properties of Styrene-Butadiene Rubbers (SBR) Filled with Industrial and Pyrolytic Carbon Blacks, and Organoclay [PDF]

open access: yes, 2017
In this work we examined effects of filler combinations (industrial carbon black (CB), pelletized pyrolytic carbon black (pCBp) and organoclay (I30.P) on the tensile mechanical and fracture mechanical properties of SBR rubbers.
Berki, Péter, Karger-Kocsis, József
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

An equivalent domain integral method for three-dimensional mixed-mode fracture problems [PDF]

open access: yes
A general formulation of the equivalent domain integral (EDI) method for mixed mode fracture problems in cracked solids is presented. The method is discussed in the context of a 3-D finite element analysis.
Raju, I. S., Shivakumar, K. N.
core   +1 more source

On the calculation of energy release rate in composites by Finite Elements, Boundary Elements and Analytical Methods [PDF]

open access: yes, 2015
To characterize a transversal crack evolution in a cross-ply [0/90]s fiber reinforced composite laminate, the associated energy release rate (ERR) was calculated by means of the J-integral embedded into the finite element method (FEM).
Curiel-Sosa, J.L.   +1 more
core   +1 more source

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