Results 91 to 100 of about 41,310,745 (318)
Some Remarks on the Annihilating-Ideal Graph of Commutative Ring with Respect to an Ideal [PDF]
Mathematics Interdisciplinary ResearchThe graph $ AG ( R ) $ {of} a commutative ring $R$ with identity has an edge linking two unique vertices when the product of the vertices equals {the} zero ideal and its vertices are the nonzero annihilating ideals of $R$.The annihilating-ideal graph ...
Zahra Mahmudiankoruie +1 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Text analysis and reader interaction [PDF]
, 1992 EFL teachers from the Brazilian public sector have often experienced difficulties in efficiently accessing the relevant information from articles published in 'English Teaching Forum'. This study attempts to investigate these difficulties from both 'text-
TEFL methods articles,
core
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Numerical Study of Weak Ferromagnetism in 2D J$\text{}_{1}$-J$\text{}_{2}$ Heisenberg Model with Dzyaloshinskii-Moriya Interaction [PDF]
, 1997 By means of exact diagonalization we consider the groundstate of the J$\text{}_{1}$-J$\text{}_{2}$ spin 1/2 Heisenberg model with an anisotropic interaction term of Dzyaloshinskii-Moriya type. We find that a Dzyaloshinskii-Moriya interaction may create a
Richter, J., Voigt, A.
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Overview of the recent experimental research on the J-TEXT tokamak
Nuclear Fusion, 2019 Abstract Recent J-TEXT research has highlighted the significance of the role that non-axisymmetric magnetic perturbations, so called three-dimensional (3D) magnetic perturbation (MP) fields, play in a fundamentally 2D concept, i.e. tokamaks.
Y. Liang +36 more
openaire +3 more sources