Results 61 to 70 of about 3,915,925 (244)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Polynomial Estimation of J-integral for Through-thickness Crack in Elastic Perfectly-Plastic Conditions

open access: yesApplications of Modelling and Simulation, 2021
Through the means of finite element analysis, J-integral for a straight through-thickness crack has been consistently reported to decrease along the crack front with the maximum and minimum values are at the midplane and the free-surface, respectively ...
Norwahida Yusoff, Feizal Yusof
doaj  

Experimental Determination and Numerical Calculation of Fracture Viscosity Criterion (J-integral)

open access: yesНаука и техника, 2005
The paper shows that it is necessary to accept energy J-integral criterion as a criterion of fracture viscosity under conditions when the zone of plasticity is rather large at crack top.
V. N. Kovalevsky   +3 more
doaj   +1 more source

Normality of Monomial Ideals [PDF]

open access: yes, 2010
Given the monomial ideal I=(x_1^{{\alpha}_1},...,x_{n}^{{\alpha}_{n}})\subset K[x_1,...,x_{n}] where {\alpha}_{i} are positive integers and K a field and let J be the integral closure of I .
Al-Ayyoub, Ibrahim
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Range of the t--J model parameters for CuO$_{2}$ plane: experimental data constraints

open access: yes, 1994
The t-J model effective hopping integral is determined from the three-band Hubbard model for the charge carriers in CuO$_{2}$ plane. For this purpose the values of the superexchange constant $J$ and the charge-transfer gap $E_{gap}$ are calculated in the
A. Auerbach   +45 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An Experimental Study on Rate Sensitivity of J-Integral and its Evaluation by Small Punch Test for TRIP Steel

open access: yesEngineering Transactions, 2014
Recently, much attention has been paid to TRIP steel since it indicates both high ductility and strength by strain induced martensitic transformation. This transformation allows TRIP steel to offer larger energy absorption than other steel at the same ...
Leishi SHI   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

An equivalent domain integral method for three-dimensional mixed-mode fracture problems [PDF]

open access: yes
A general formulation of the equivalent domain integral (EDI) method for mixed mode fracture problems in cracked solids is presented. The method is discussed in the context of a 3-D finite element analysis.
Raju, I. S., Shivakumar, K. N.
core   +1 more source

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