Results 61 to 70 of about 3,915,925 (244)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Through the means of finite element analysis, J-integral for a straight through-thickness crack has been consistently reported to decrease along the crack front with the maximum and minimum values are at the midplane and the free-surface, respectively ...
Norwahida Yusoff, Feizal Yusof
doaj
Experimental Determination and Numerical Calculation of Fracture Viscosity Criterion (J-integral)
The paper shows that it is necessary to accept energy J-integral criterion as a criterion of fracture viscosity under conditions when the zone of plasticity is rather large at crack top.
V. N. Kovalevsky +3 more
doaj +1 more source
Normality of Monomial Ideals [PDF]
Given the monomial ideal I=(x_1^{{\alpha}_1},...,x_{n}^{{\alpha}_{n}})\subset K[x_1,...,x_{n}] where {\alpha}_{i} are positive integers and K a field and let J be the integral closure of I .
Al-Ayyoub, Ibrahim
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Range of the t--J model parameters for CuO$_{2}$ plane: experimental data constraints
The t-J model effective hopping integral is determined from the three-band Hubbard model for the charge carriers in CuO$_{2}$ plane. For this purpose the values of the superexchange constant $J$ and the charge-transfer gap $E_{gap}$ are calculated in the
A. Auerbach +45 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Recently, much attention has been paid to TRIP steel since it indicates both high ductility and strength by strain induced martensitic transformation. This transformation allows TRIP steel to offer larger energy absorption than other steel at the same ...
Leishi SHI +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
An equivalent domain integral method for three-dimensional mixed-mode fracture problems [PDF]
A general formulation of the equivalent domain integral (EDI) method for mixed mode fracture problems in cracked solids is presented. The method is discussed in the context of a 3-D finite element analysis.
Raju, I. S., Shivakumar, K. N.
core +1 more source

