Results 71 to 80 of about 392,474 (265)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Buenos Aires Stroke School: a path to continuous medical education in stroke, empowering and connecting future specialists in vascular neurology across Latin America

Journal of Stroke and Cerebrovascular Diseases
Background: The Buenos Aires Stroke School was established in 2019 to address the unmet need for structured, high-quality stroke education in Latin America.
Matías J. Alet, Raúl C. Rey, Sebastián F. Ameriso   +2 more
doaj   +1 more source

Effect of Strain Hardening on the Estimation of J-Integral in Compact Tension Specimens

Journal of King Saud University: Engineering Sciences, 2004
Compact tension (CT) specimen testing is used to compute the fracture toughness parameter J-integral for different materials using load-displacement curve. In this work, J is investigated for compact tension specimen for a strain-hardening material using
A. Al-Abduljabbar
doaj   +1 more source

A Study on J-Integral as a Fracture Criterion

Journal of the Society of Naval Architects of Japan, 1975
The J-integral has been proposed as an engineering fracture criterion for elastic-plastic behavior in metals.The J-integral, as is defined, has several advantages over some other currently used fracture parameters. But the experimental evidence so far obtained to show its practical usefulness have been limited.Using an ordinary ship steel, the authors ...
Kanazawa, Takeshi, Machida, Susumu, Kaneda, Shigehiro, Onozuka, Masakazu   +3 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A J-INTEGRAL MEASUREMENT METHOD BASED ON DIGITAL IMAGE CORRELATION

Jixie qiangdu, 2018
J-integral is an important fracture parameter which quantitatively describes the stress and strain fields near a crack tip. Accurate and efficient measurement of J-integral is of great significance for the evaluation of crack stability and propagation in
JIANG Wei, JIANG XianFeng, HUANG YuLong
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Solvability of Volterra integral equations of third kind by modified Bernstein operators

Journal of Inequalities and Applications
In this paper, we apply modified Bernstein operators B m ∗ ( f ) $B^{*}_{m}(f)$ to obtain the solution of Volterra integral equations of third type.
Petro Bwire, Santosh Kumar, Mohammad Mursaleen   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source