Results 11 to 20 of about 73 (70)

Cancer inequalities in incidence and mortality in the State of São Paulo, Brazil 2001–17

open access: yesCancer Medicine, Volume 12, Issue 15, Page 16615-16625, August 2023., 2023
We noted marked increases in incidence rates with increasing SES in the municipality of São Paulo for cancers of the colorectum, lung, female breast, and prostate. For female breast, lung, and to some extent colorectal cancer, both incidence and mortality rates uniformly rose with increasing SES, whereas for cervical cancer, both incidence and ...
Adeylson Guimarães Ribeiro   +5 more
wiley   +1 more source

Exploring the Therapeutic Potential of Traditional Antimalarial and Antidengue Plants: A Mechanistic Perspective

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2023, Issue 1, 2023., 2023
Malaria, a highly perilous infectious disease, impacted approximately 230 million individuals globally in 2019. Mosquitoes, vectors of over 10% of worldwide diseases, pose a significant public health menace. The pressing need for novel antimalarial drugs arises due to the imminent threat faced by nearly 40% of the global population and the escalating ...
Chinnaperumal Kamaraj   +13 more
wiley   +1 more source

Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS‐Induced Neuroinflammation by Interfering in the TLR4/NF‐κB‐MAPK Signaling Pathway in Microglial Cells

open access: yesOxidative Medicine and Cellular Longevity, Volume 2023, Issue 1, 2023., 2023
Neuroinflammation is present in the pathophysiological mechanisms of several diseases that affect the central nervous system (CNS). Microglia have a prominent role in initiating and sustaining the inflammatory process. Epiisopiloturine (EPI) is an imidazole alkaloid obtained as a by‐product of pilocarpine extracted from Pilocarpus microphyllus ...
João Antônio Costa de Sousa   +8 more
wiley   +1 more source

Doxycycline Hyclate Modulates Antioxidant Defenses, Matrix Metalloproteinases, and COX‐2 Activity Accelerating Skin Wound Healing by Secondary Intention in Rats

open access: yesOxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021
The main objective of this study was to investigate the action of doxycycline hyclate (Dx) in the skin wound healing process in Wistar rats. We investigated the effect of Dx on inflammatory cell recruitment and production of inflammatory mediators via in vitro and in vivo analysis.
Luciana S. Altoé   +8 more
wiley   +1 more source

A practical approach to measuring the biodiversity impacts of land conversion

open access: yesMethods in Ecology and Evolution, Volume 11, Issue 8, Page 910-921, August 2020., 2020
Abstract Further progress in reducing biodiversity loss relies on the improved quantification of the connections between drivers of habitat loss and subsequent biodiversity impacts. To this end, biodiversity impact metrics should be able to report linked trends in specific human activities and changes in biodiversity state, accounting for both the ...
América P. Durán   +7 more
wiley   +1 more source

Branch regeneration of jaborandi submitted to diferentes types of pruning and cropping systems

open access: yesActa Agronómica
 The leaf of the jaborandi (Pilocarpus microphyllus) is the part of the plant of economic interest, from which the pilocarpine is extracted, therefore, leaf production is the main variable that determines the productivity of this species.
Osmar Alves Lameira   +4 more
doaj   +1 more source

Local Knowledge and Conservation Priorities of Medicinal Plants near a Protected Area in Brazil

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
We investigated the influence of socioeconomic factors (age, gender, and occupation) on the local knowledge of medicinal plants in the Araripe National Forest, Brazil, and the priority of conservation of the species as perceived by people. Additionally, priority species for in situ conservation were identified by calculating conservation priority (CP).
Noelia Ferreira da Silva   +6 more
wiley   +1 more source

Morfoanatomia dos órgãos vegetativos de Piper crassinervium H.B. & K. (Piperaceae) Morphology and anatomy of vegetative organs of Piper crassinervium H.B. & K. (Piperaceae)

open access: yesActa Botânica Brasílica, 2005
Objetivando auxiliar trabalhos taxonômicos e farmacobotânicos, foram realizados estudos morfoanatômicos dos órgãos vegetativos de Piper crassinervium H.B. & K. (jaborandi). O material foi analisado seguindo-se técnicas usuais de corte e coloração.
Adriana Lenita Meyer Albiero   +3 more
doaj   +1 more source

Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2017
Supercritical fluid extraction was used to extract the alkaloid N‐[7‐(3′,4′‐methylenedioxyphenyl)‐2(Z),4(Z)‐heptadienoyl]pyrrolidine from leaves of Piper amalago L. A three‐level orthogonal array design matrix, OAD OA9(34), was used for optimization of the parameters of supercritical extraction of the alkaloid, employing supercritical carbon dioxide ...
V. S. Carrara   +7 more
wiley   +1 more source

Sustainability of Jaborandi in the eastern Brazilian Amazon

open access: yesPerspectives in Ecology and Conservation, 2017
The genus Pilocarpus (Rutaceae) includes the only known species able to synthesize pilocarpine, an imidazole alkaloid largely employed in glaucoma and xerostomia treatments.
Cecilio Frois Caldeira   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy