Results 31 to 40 of about 1,611,821 (178)

Vaginal Laser Treatment for Genitourinary Syndrome of the Menopause: A Dose-Determining Study in Breast Cancer Survivors. [PDF]

Lasers Surg Med
ABSTRACT Objectives Breast cancer survivors (BCSs) receiving endocrine therapy frequently develop genitourinary syndrome of menopause, characterized by vaginal dryness, pain, and urinary symptoms. Fractional CO2 vaginal laser therapy has been proposed as a non‐hormonal management option, but the optimal number of treatment sessions remains unclear.
Jacobsen S, Glavind-Kristensen M, Jensen AB, Forman A, Bertelsen VM, Bor P.   +5 more
europepmc   +2 more sources

Slow calcium removal contributes to impaired lusitropic response to β-adrenergic stimulation in HFpEF mice. [PDF]

J Physiol
Abstract figure legend Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart failure, yet major gaps remain in our understanding of its underlying mechanisms, disease progression and effective treatment strategies. Mice with HFpEF exhibited exercise intolerance and diastolic dysfunction in vivo, while isolated hearts ...
Zawadzki T, Usai DS, Kaad SG, Rasmussen KH, Larsen MS, Jacobsen JCB, Thomsen MB.   +6 more
europepmc   +2 more sources

A ring D chromosome in association with Down's syndrome-like phenotype

Arquivos de Neuro-Psiquiatria, 1973
The case of a ten-years-old mentally retarded girl with Down's syndrome-like features whose chromosome analysis revealed an unusual mosaicism including 10% mitosis with a ring chromosome replacing a D chromosome is reported.
A. Wajntal, A. J. Diament, P. H. Saldanha   +2 more
doaj   +3 more sources

Submicroscopic deletions of 11q24-25 in individuals without Jacobsen syndrome: re-examination of the critical region by high-resolution array-CGH

Molecular Cytogenetics, 2008
Background Jacobsen syndrome is a rare contiguous gene disorder that results from a terminal deletion of the long arm of chromosome 11. It is typically characterized by intellectual disability, a variety of physical anomalies and a distinctive facial ...
VanAllen Margot I, Costa Teresa, McLeod Ross, Dyack Sarah, Gibson William, Clarke Lorne, Chudley Albert E, Arbour Laura, Farrell Sandra A, McGillivray Barbara, Bernier Francois P, Liu Xudong, Harvard Chansonette, Qiao Ying, Tyson Christine, Yong Siu-li, Graham Gail E, MacLeod Patrick, Patel Millan S, Hurlburt Jane, Holden Jeanette JA, Lewis Suzanne ME, Rajcan-Separovic Evica   +22 more
doaj   +1 more source

FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migrations

iScience, 2023
Summary: Mutations in the human fasciculation and elongation protein zeta 1 (FEZ1) gene are found in schizophrenia and Jacobsen syndrome patients. Here, using human cerebral organoids (hCOs), we show that FEZ1 expression is turned on early during brain ...
Yinghua Qu, Jonathan Jun-Yong Lim, Omer An, Henry Yang, Yi-Chin Toh, John Jia En Chua   +5 more
doaj   +1 more source

Molecular cytogenetic characterization of Jacobsen syndrome (11q23.3-q25 deletion) in a fetus associated with double outlet right ventricle, hypoplastic left heart syndrome and ductus venosus agenesis on prenatal ultrasound

Taiwanese Journal of Obstetrics & Gynecology, 2017
Objective: We present molecular cytogenetic characterization of Jacobsen syndrome (11q23.3-q25 deletion) in a fetus associated with double outlet right ventricle (DORV), hypoplastic left heart syndrome (HLHS), and ductus venosus (DV) agenesis on prenatal
Chih-Ping Chen, Liang-Kai Wang, Pei-Chen Wu, Tung-Yao Chang, Schu-Rern Chern, Peih-Shan Wu, Yen-Ni Chen, Shin-Wen Chen, Chen-Chi Lee, Chien-Wen Yang, Wayseen Wang   +10 more
doaj   +1 more source

Jacobsen syndrome: Chromosome deletion at llq23

Journal of Osteopathic Medicine, 1998
Abstract A male infant delivered at term to unrelated parents was found to have multiple dysmorphic facial characteristics, abnormal head shape, anemia, thrombocytopenia, a prominent holosystolic heart murmur with multiple cardiac defects, hypotonia, and was small for his gestational age.
Daniel R, Clang, Richard J, LaBaere Ii
openaire   +2 more sources

Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration

Frontiers in Cell and Developmental Biology, 2021
Down Syndrome (DS) Cell Adhesion Molecules (DSCAMs) are transmembrane proteins of the immunoglobulin superfamily. Human DSCAM is located within the DS critical region of chromosome 21 (duplicated in Down Syndrome patients), and mutations or copy-number ...
Manuela D. Mitsogiannis, Anna Pancho, Tania Aerts, Sonja M. Sachse, Ria Vanlaer, Lut Noterdaeme, Dietmar Schmucker, Dietmar Schmucker, Eve Seuntjens   +8 more
doaj   +1 more source

The psychosocial toll of Dublin III on asylum seekers in the Netherlands

American Journal of Community Psychology, EarlyView.
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley   +1 more source

Hugh Newell Jacobsen Guest Lecture

, 1993
Architectural projects and/or sites mentioned: Palace of Minos (2000 B.C.E. - 1400 B.C.E.) (Knossos, Greece) ; Piedmont (Lehrer House) (Hugh Newell Jacobsen, 1735/1989-1990) (Charles Town, West Virginia) ; Hillside House (Hugh Newell Jacobsen and Andrea ...
Jacobsen, Hugh Newell
core   +1 more source