Results 1 to 10 of about 958,876 (227)
Strongly correlated and topological states in [111] grown transition metal oxide thin films and heterostructures [PDF]
APL Materials, 2020 We highlight recent advances in the theory, materials fabrication, and experimental characterization of strongly correlated and topological states in [111] oriented transition metal oxide thin films and heterostructures, which are notoriously difficult ...
Jak Chakhalian +2 more
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Immunological Medicine, 2023 Among various tyrosine kinases, a family of Janus kinases (JAK) has been elucidated as key players in signal transduction from vital cytokine receptors, such as interleukins and interferons.
Hideto Kameda
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Jak dál — aneb jak pomáhat vedení škol?
Pedagogická Orientace, 2018 N ...
Václav Klapal
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Roles of non-receptor tyrosine kinases in pathogenesis and treatment of depression [PDF]
Journal of Integrative Neuroscience, 2022 Major depressive disorder is a chronic psychiatric disease with a high prevalence. Brain mechanisms for depression at cellular and molecular levels are far from clear. Increasing evidence from clinical and preclinical studies reveals critical roles of
John Q. Wang +4 more
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The JAK/STAT signaling pathway: from bench to clinic
Signal Transduction and Targeted Therapy, 2021 The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular processes, the JAK/STAT pathway constitutes a rapid membrane-to-nucleus ...
Xiaoying Hu +4 more
semanticscholar +1 more source
Evolving cognition of the JAK-STAT signaling pathway: autoimmune disorders and cancer
Signal Transduction and Targeted Therapy, 2023 The Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathway is an evolutionarily conserved mechanism of transmembrane signal transduction that enables cells to communicate with the exterior environment.
Chen Xue +8 more
semanticscholar +1 more source
JAK/STAT pathway: Extracellular signals, diseases, immunity, and therapeutic regimens
Frontiers in Bioengineering and Biotechnology, 2023 Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were originally thought to be intracellular signaling pathways that mediate cytokine signals in mammals.
Q. Hu +8 more
semanticscholar +1 more source
Platelets, 2022 Several Janus kinase (JAK) inhibitors (jakinibs) have recently been approved to treat inflammatory, autoimmune and hematological conditions. Despite emerging roles for JAKs and downstream signal transducer and activator of transcription (STAT) proteins ...
Iván Parra-Izquierdo +9 more
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Platelets, 2023 Platelet transfusion refractoriness (PTR) is an intractable issue in hematological patients, which increases bleeding risks and hospitalization costs to a great extent.
Xiaofei Song +6 more
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Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy
Archives of Medical Science, 2023 Introduction Diabetic nephropathy (DN) is a leading cause of kidney failure. Lysozyme (LYZ) is an essential component of innate immunity and exhibits antibacterial properties.
Yan Ren +4 more
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