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Clonal Hematopoiesis of Indeterminate Potential (CHIP): A Model of Mutation-Driven Thromboinflammation. [PDF]
Malkots B +9 more
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On the prenatal origins of the myeloproliferative neoplasms. [PDF]
Langabeer SE.
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Toward new therapy end points in polycythemia vera: targeting clonal and inflammatory pathways. [PDF]
Barbui T, Scandura JM.
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Polycythemia Vera with Incidental Large Aortic Aneurysm and Giant Cell Arteritis: Case Report. [PDF]
Obaid K +8 more
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Absence of JAK2 V617F mutation in thalassemia intermedia patients
Molecular Biology Reports, 2008JAK2 is a cytoplasmic tyrosine kinase that has a vital role in signal transduction from several hemopoietic growth factor receptors. The JAK2 V617F mutation has been implicated in a variety of diseases mainly related to myeloproliferative disorders including polycythemia Vera, essential thrombocythemia, and idiopathic Myelofibrosis but has not been ...
Ali Taher, Rami Mahfouz, Zaher Otrock
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Insights into JAK2-V617F mutation in CML
The Lancet Oncology, 2007a case of JAK2-V617F mutation is CML.
Monica Bocchia +8 more
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The V617F JAK2 mutation and the myeloproliferative disorders
Hematological Oncology, 2005AbstractThe discovery this year of a single mutation in the Janus Kinase (JAK)‐2 gene in a high percentage of cases of polycythaemia vera (PV), essential thrombocythaemia (ET) and myelofibrosis suggests that it maybe the underlying molecular mechanism for these disorders.
Percy, M.J., McMullin, Mary
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