Results 51 to 60 of about 199,620 (187)

Structural modeling of sexual performance in postmenopausal women based on sexual schemas with the mediator role of state-trait anxiety and sexual self-esteem [PDF]

مجله علوم روانشناختی, 2023
Background: Sexual performance based on sexual schemas is one of the important aspects in personal health. However, in all reviewed researches, the role of trait state anxiety and sexual self-esteem as mediating variables has not been considered and that
Seyede Parisa Mojtahedzadeh, Saeid Teimory, Mahdi Nayyeri, Adele Isanazar   +3 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effect of Emotionally Focused Couple Therapy on Attachment Behavior and Marital Intimacy in Patients with Coronary Artery Disease [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Today, coronary artery disease (CVD) is one of the world's most common disorders, and prevention is the key to controlling the disease.
Fereshteh Oladi, Ali Akbar Saremi, Ali Eshraghi, Mohammad Hossein Karbalaee   +3 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Comparison of computer-based cognitive stimulation efficacy with and without transcranial direct current stimulation (tDCS) on the quality of life of patients recovered from Covid-19 [PDF]

مجله علوم روانشناختی
Background: Post-COVID-19 neurological sequelae may have a long-term negative impact on cognitive functions and quality of life in recovered patients.
Alireza Lotfi, Alireza rajaei, mahdi Nayyeri   +2 more
doaj  

The efficacy of mindfulness-based stress reduction program on disease perception in thalassemia patients

مجله علوم روانشناختی, 2022
Background: Disease perception is an organized cognitive representation that thalassemia patients have of their illness and its effects. Research has shown that mindfulness-based stress reduction programs are effective on self-management and reducing ...
Fatemeh Akbari Gelvardi, Saeed Teimory, Alireza Rajaei   +2 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Effectiveness of Emotion-Focused Therapy on Psychological Security in Women Involved in Domestic Violence [PDF]

Iranian Journal of Educational Research
Objective: The present investigation aimed to examine the efficacy of emotion-focused therapy in relation to the perception of psychological security and its components in women affected by domestic violence.
Tahereh Yarmohammadi, Saeed Teymouri, Alireza Rajaei   +2 more
doaj