Results 71 to 80 of about 199,620 (187)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
INFLUENCE OF ICE JAM AND RIVER NARROWING IN KENUFUCHI RIVER [PDF]
, 2019 On 9th March, 2018, due to unusual rainfall and temperature rise, ice jam occurred in the Kenufuchi River which has never been seen before. In the future, it is foreseen that water disaster will become more frequent with climate change, and rivers where ...
横山, 洋 +12 more
core
JAM-C is ubiquitylated by the E3 ligase CBL.
, 2019 (A–G) HUVECs were transfected with 2 different CBL siRNAs over a 96-h period. (A) Cells were lysed and analysed by SDS-PAGE and western blot, detecting CBL and tubulin. Knockdown was typically ≥90%. (B–E) Untreated or CBL knockdown cells were transfected
Vinothini Rajeeve (4257748) +9 more
core +1 more source
, 2020 BERPUASA selama 19 jam. Kedengarannya macam tidak percaya, tetapi itu yang dilalui sesetengah umat Islam terutama di benua Eropah yang berpuasa dalam tempoh amat ...
fazurawati, Che Lah
core +2 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Jurnal Aplikasi ManajemenCorrigendum to “The Role of Women Merchants in Increasing Family’s Income (A Case Study on Indigenous Papuan Women Merchants)“ [JAM: Jurnal Aplikasi Manajemen, 14(4), 641-649]
JAM JAM
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
JAM-C is constitutively trafficked from endothelial cell junctions.
, 2019 (A) Schematic of the endocytosis of endogenous JAM-C from the endothelial cell surface showing the extracellular immunoglobulin domains (blue) and the intracellular PDZ interacting domain (clear circle).
Vinothini Rajeeve (4257748) +9 more
core +1 more source