Results 61 to 70 of about 1,078,243 (279)

Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection [PDF]

Cells, 2018
Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin superfamily. JAMs are involved in a variety of biological processes both in the adult organism but also during development. These include processes such as inflammation, angiogenesis, hemostasis, or epithelial barrier formation, but also developmental ...
Daniel Kummer, Klaus Ebnet
openaire   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Determinants of Capital Structure and Performance in Listed Companies of Tehran Stock Exchange [PDF]

International Journal of Management, Accounting and Economics, 2018
This study examines the determinants of capital structure and performance in the listed companies of Tehran Stock Exchange. Information of the financial statements of the sample companies were extracted using Rahavardnovin Software.
Mina Jami, Amir Koloukhi
doaj  

Effectiveness of acceptance and commitment therapy on emotion regulation in epileptic patients

Social Determinants of Health, 2021
Background: Epilepsy can severely affect cognitive-emotional and behavioral function. Using an appropriate treatment method to deal with it in order to treat emotional disorders can be an effective action due to the importance of this disorder.
Hamideh Sadeghnezhad, Saeed Teimory, Mehdi Amiri   +2 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Effect of Emotionally Focused Couple Therapy on Attachment Behavior and Marital Intimacy in Patients with Coronary Artery Disease [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Today, coronary artery disease (CVD) is one of the world's most common disorders, and prevention is the key to controlling the disease.
Fereshteh Oladi, Ali Akbar Saremi, Ali Eshraghi, Mohammad Hossein Karbalaee   +3 more
doaj  

Grammar Jam: Adding a Creative Editing Tactic [PDF]

, 2018
The author argues reading, hearing, and then composing musical lyrics involving grammatical concerns can help college writing students to edit more effectively for a song\u27s grammar topic.
Gillespie, David
core   +1 more source

Magnetic Jam in the Corona of the Sun

, 2015
The outer solar atmosphere, the corona, contains plasma at temperatures of more than a million K, more than 100 times hotter that solar surface. How this gas is heated is a fundamental question tightly interwoven with the structure of the magnetic field ...
Bingert, S., Chen, F., Cheung, M. C. M., Peter, H.   +3 more
core   +1 more source

A novel antibacterial peptide derived from Crocodylus siamensis haemoglobin hydrolysate induces membrane permeabilization causing iron dysregulation, oxidative stress and bacterial death [PDF]

, 2017
Aims A novel antibacterial peptide from Crocodylus siamensis haemoglobin hydrolysate (CHH) was characterized for antimicrobial activity. Methods and Results CHHs were hydrolysed for 2 h (2 h-CHH), 4 h (4h-CHH), 6 h (6 h-CHH) and 8 h (8 h-CHH). The
Adje, Ali, Arroume, Arroume, Chitemerere, Daoud, Froidevaux, Gault, Jandaruang, Jangpromma, Kabbua, Maddocks, Maijaroen, Mbah, Michel, Miller, Osman, Pakdeesuwan, Pata, Phosri, Phosri, Sato, Schwyn, Solanky, Song, Srihongthong, Vasilchenko, Winkelmann, Yu, Zheng   +29 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source