IgE Hyperproduction Through Enhanced Tyrosine Phosphorylation of Janus Kinase 3 in NC/Nga Mice, a Model for Human Atopic Dermatitis [PDF]
, 1999 Masahiro Matsumoto +10 more
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Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers
Cancer Science, EarlyView.Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu +5 more
wiley +1 more source
Pharmacological inhibition of the Janus Kinases enhances ASCL1 protein stability and transcriptional activity [PDF]
Maya A. Hanspal +4 more
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Curcumin Suppresses Janus Kinase-STAT Inflammatory Signaling through Activation of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 in Brain Microglia [PDF]
, 2003 Hak Yong Kim +3 more
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Contact Dermatitis, EarlyView.Patient‐reported outcomes are an important complement to physician‐assessed clinical outcome measures in Chronic Hand Eczema. In a pooled analysis of two randomised, controlled trials, twice‐daily treatment with delgocitinib cream 20 mg/g significantly improved the health‐related quality of life of patients with moderate to severe Chronic Hand Eczema ...
Andrea Bauer +7 more
wiley +1 more source
Comparative safety of oral Janus kinase inhibitors versus dupilumab in patients with atopic dermatitis: A population-based cohort study [PDF]
Serena Yun‐Chen Tsai +5 more
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Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor [PDF]
, 2007 Akihiro Muto +12 more
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JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Erosive pustular dermatosis of the lower legs (EPDL) is a rarely diagnosed, chronic inflammatory skin disease that occurs predominantly in elderly people. Predisposing factors include skin atrophy, chronic venous insufficiency, and trauma. Although the pathogenesis of EPDL has not yet been conclusively clarified, there are ongoing discussions ...
Joachim Dissemond +3 more
wiley +1 more source
Clinical and laboratory presentations of Janus Kinase II-positive patients in Saudi population
, 2014 Hafiz Malhan +5 more
openalex +1 more source