Results 191 to 200 of about 117,631 (302)

JI‐CJ002 and Dabrafenib Combination Enhances Antitumor Activity in Melanoma Associated With the Downregulation of B7‐H3

Cancer Science, EarlyView.
Schematic pathway diagram illustrating the effects of JI‐CJ002 and dabrafenib on melanoma progression. The combination of JI‐CJ002 and dabrafenib is associated with reduced B7‐H3 expression and modulation of signaling pathways implicated in melanoma progression, including JAK2/STAT3, PI3K/AKT/mTOR, and Rb/E2F1.
Sang‐Eun Lee, Young Ha Kim, Bo Shin Heo, Chunhoo Cheon, Seong‐Gyu Ko   +4 more
wiley   +1 more source

Research progress in electrochemical determination of Janus kinase inhibitors and proposals for amplifying clinical applicability. [PDF]

Mikrochim Acta
Mikus P, Hanko M, Zelinkova Z, Labuda J.
europepmc   +1 more source

From Sprinters to Marathoners: Rethinking Therapeutic Speed and Disease Modification in Atopic Dermatitis

Allergy, EarlyView.
Thomas Bieber, Felix Lauffer
wiley   +1 more source

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

Cancer Science, EarlyView.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka, Shuhei Hirose, Yu Wang, Tomonori Yaguchi, Kenji Chamoto   +4 more
wiley   +1 more source

Acute retinal necrosis during the systemic use of Janus kinase inhibitor. [PDF]

Int J Retina Vitreous
Watanabe D, Namba K, Hase K, Suzuki K, Ogino Y, Saito M, Iwata D, Mizuuchi K, Hiraoka M, Narita M, Kitaichi N, Kitaya N, Ishida S.   +12 more
europepmc   +1 more source

Short-term omalizumab as a potential rescue therapy for alopecia areata flares during Janus kinase inhibitor maintenance. [PDF]

JAAD Int
Wang Q, Cheng K, Lin JM, Tao K, Xu M, Zhang X, Tang S, Ni C, Wu W, Lin J.   +9 more
europepmc   +1 more source

Janus kinase (JAK) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Janus kinase inhibitors clear to land [PDF]

Rheumatology, 2017
openaire   +2 more sources

Effect of Delgocitinib Cream on Health‐Related Quality of Life in Patients With Moderate to Severe Chronic Hand Eczema

Contact Dermatitis, EarlyView.
Patient‐reported outcomes are an important complement to physician‐assessed clinical outcome measures in Chronic Hand Eczema. In a pooled analysis of two randomised, controlled trials, twice‐daily treatment with delgocitinib cream 20 mg/g significantly improved the health‐related quality of life of patients with moderate to severe Chronic Hand Eczema ...
Andrea Bauer, Lyn Guenther, Richard Woolf, Eydna Didriksen Apol, Douglas Maslin, Nanna Nyholm, Henrik Thoning, Marie Louise Schuttelaar   +7 more
wiley   +1 more source

Efficacy of Janus kinase inhibitors in the treatment of acute exacerbations of rheumatoid arthritis-associated interstitial lung disease: a retrospective observational case series. [PDF]

Front Immunol
Okamoto M, Fujikawa K, Mihara T, Doi S, Tomari S, Koga T, Kido T, Sakamoto N, Mizokami A, Mukae H, Kawakami A.   +10 more
europepmc   +1 more source