Results 81 to 90 of about 73,979 (245)

Interface‐Engineered MXene/g‐C3N4 Heterostructures for Energy and Environmental Applications

EcoEnergy, EarlyView.
This review highlights how interface engineering in MXene/g‐C3N4 heterostructures regulates charge transfer, band alignment, and surface chemistry, enabling broad applications in photocatalytic conversion, environmental remediation, energy storage, and multifunctional sensing/therapy. ABSTRACT Two‐dimensional MXene/g‐C3N4 heterostructures have recently
Feng Wang, Geng Liu, Xiaoqiang An
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Experimental Pharmacological Management of Psoriasis

Journal of Experimental Pharmacology, 2021
Elena Campione,1 Terenzio Cosio,1 Monia Di Prete,2 Caterina Lanna,1 Annunziata Dattola,1 Luca Bianchi1 1Dermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, 00133, Italy; 2Anatomic Pathology, University of Rome Tor ...
Campione E, Cosio T, Di Prete M, Lanna C, Dattola A, Bianchi L   +5 more
doaj  

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Successful treatment of recalcitrant follicular lichen planus (lichen planopilaris) with the topical JAK 1/2 inhibitor ruxolitinib

JEADV Clinical Practice
We report the successful treatment of a patient with refractory follicular lichen planus (LP) with topical ruxolitinib, a Janus kinase (JAK) 1/2 inhibitor, which resulted in significant improvement of lesional skin within 1 month of daily use.
Tanja Fetter, Dagmar Wilsmann‐Theis, Luka deVos‐Hillebrand, Natalija Novak, Joerg Wenzel   +4 more
doaj   +1 more source

Gut Microbiota Modulation and Functional Effects of Edible and Medicinal Fungi: Sanghuangporus vaninii as a Case Study

Gut Medicine, EarlyView.
ABSTRACT Edible and medicinal fungi exert diverse biological effects, including immunomodulatory, antitumour, and anti‐inflammatory activities, as well as the amelioration of metabolic disorders. The relationship between these effects and the gut microbiota is attracting increasing attention.
Meng Teng, Wenqi Li, Di Wang, Lanzhou Li
wiley   +1 more source

Role of Janus kinase 1 and signal transducer and activator of transcription 3 in vitiligo.

Clinical, cosmetic and investigational dermatology, 2019
Vitiligo is an acquired autoimmune skin disorder. The often-visible lesions of vitiligo have a major impact on patients' quality of life and the results of the treatment regimens on offer are unsatisfactory, so there is a need for new therapeutic regimens.
Samaka,Rehab M., Basha,Mohammed A., Menesy,Dina   +2 more
openaire   +3 more sources

Comprehensive kinase profile of pacritinib, a nonmyelosuppressive Janus kinase 2 inhibitor

Journal of Experimental Pharmacology, 2016
Jack W Singer,1 Suliman Al-Fayoumi,1 Haiching Ma,2 Rami S Komrokji,3 Ruben Mesa,4 Srdan Verstovsek5 1Translational Medicine, CTI BioPharma Corp., Seattle, WA, 2Department of Research and Development, Reaction Biology, Malvern, PA, 3Department of ...
Singer J, Al-Fayoumi S, Ma H, Komrokji R, Mesa R, Verstovsek S   +5 more
doaj  

The Burden of Alopecia Areata and Management with Baricitinib in the United Arab Emirates: A Narrative Review

Dermatology and Therapy
Alopecia areata is an inflammatory autoimmune disease that presents as non-scarring hair loss in adults and children and causes substantial psychological distress, economic burden, and reduced quality of life for those affected.
Hussein Abdel Dayem, Anwar Al Hammadi, Ashraf Reda, Fatima Albreiki, Ayman Al Naeem, Ahmed Ameen, Mohamed Ahmed, Huda Rajab Ali, Mohamed Elrayes, Gozde Senay, Muna Al Murrawi   +10 more
doaj   +1 more source

Successful Treatment of Anti-Jo-1 Positive Inflammatory Myopathy With Tofacitinib

Case Reports in Rheumatology
Idiopathic inflammatory myopathies are, in some cases, refractory to all guideline-based treatments, posing a very difficult challenge in clinical practice.
Janis Timsans, Anna-Mari Hokkanen, Joonas Rautavaara, Anne Kerola, Sanna Huovinen, Markku Kauppi   +5 more
doaj   +1 more source