Results 231 to 240 of about 453,251 (315)

Erosive pustular dermatosis of the lower legs (EPDL): A rarely diagnosed neutrophilic dermatosis of the elderly

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Erosive pustular dermatosis of the lower legs (EPDL) is a rarely diagnosed, chronic inflammatory skin disease that occurs predominantly in elderly people. Predisposing factors include skin atrophy, chronic venous insufficiency, and trauma. Although the pathogenesis of EPDL has not yet been conclusively clarified, there are ongoing discussions ...
Joachim Dissemond, Jan Kottner, Jan‐Malte Placke, Cornelia Erfurt‐Berge   +3 more
wiley   +1 more source

Long non-coding RNA JPX promotes endometrial carcinoma progression via janus kinase 2/signal transducer and activator of transcription 3. [PDF]

Front Oncol
Xiong H, Zhang W, Xie M, Chen R, Chen H, Lin Q.   +5 more
europepmc   +1 more source

Vitamin D Deficiency and Janus kinase 2 V617F Mutation Status in Essential Thrombocythemia and Polycythemia Vera. [PDF]

Malays J Med Sci, 2020
Yikilmaz AŞ, Akinci S, Bakanay ŞM, Dilek İ.   +3 more
europepmc   +1 more source

Long non-coding RNA musculin antisense RNA 1 promotes proliferation and suppresses apoptosis in osteoarthritic chondrocytes via the microRNA-369-3p/Janus kinase-2/ signal transducers and activators of transcription 3 axis. [PDF]

Bioengineered, 2022
Tang Z, Gong Z, Sun X.
europepmc   +1 more source

Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors.

ACS Medicinal Chemistry Letters, 2015
A. C. Hart, Gretchen M. Schroeder, H. Wan, J. Grebinski, J. Inghrim, J. Kempson, Junqing Guo, W. Pitts, J. Tokarski, J. Sack, Javed A Khan, J. Lippy, M. V. Lorenzi, D. You, T. Mcdevitt, R. Vuppugalla, Yueping Zhang, L. Lombardo, G. Trainor, A. Purandare   +19 more
semanticscholar   +1 more source

An international consensus on screening and monitoring early‐stage type 1 diabetes: A roadmap to European implementation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease that results in loss of insulin‐secreting pancreatic β‐cells in the islets of Langerhans. A diagnosis of T1D is typically associated with children and adolescents, yet half of all diagnoses of T1D are made in adults.
Sufyan Hussain, Timothy Tree, Chantal Mathieu, Tomasz Klupa, Anna‐Kaisa Tuomaala, Maartje de Wit, Olga Kordonouri, Katarina Braune, Jaivir Pall, Luis Castano, Rachel E. J. Besser, Júlia Galhardo, Francesca Ulivi, Emanuele Bosi, Uroš Bogdanovic, Coralie Alabert, Tadej Battelino   +16 more
wiley   +1 more source

Patient-reported Effects of Fedratinib, an Oral, Selective Inhibitor of Janus Kinase 2, on Myelofibrosis-related Symptoms and Health-related Quality of Life in the Randomized, Placebo-controlled, Phase III JAKARTA Trial. [PDF]

Hemasphere, 2021
Mesa RA, Schaap N, Vannucchi AM, Kiladjian JJ, Passamonti F, Zweegman S, Talpaz M, Verstovsek S, Rose S, Abraham P, Lord-Bessen J, Tang D, Guo S, Ye X, Harrison CN.   +14 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Homeodomain-containing gene 10 contributed to breast cancer malignant behaviors by activating Interleukin-6/Janus kinase 2/Signal transducer and activator of transcription 3 pathway.

Bioengineered, 2022
Shen J, Wang M, Li F, Yan H, Zhou J.
europepmc   +1 more source

Janus kinase 2/signal transducer and activator of transcription 3 inhibitors attenuate the effect of cardiotrophin-like cytokine factor 1 and human focal segmental glomerulosclerosis serum on glomerular filtration barrier.

Translational research : the journal of laboratory and clinical medicine, 2015
Mukut Sharma, Jianping Zhou, J. Gauchat, Ramratan Sharma, E. McCarthy, T. Srivastava, V. Savin   +6 more
semanticscholar   +1 more source