Results 341 to 350 of about 457,473 (371)

Expression, purification, and characterization of TYK-2 kinase domain, a member of the Janus kinase family

Biochemical and Biophysical Research Communications, 2010
The Janus kinase family consists of four members: JAK-1, -2, -3 and TYK-2. While JAK-2 and JAK-3 have been well characterized biochemically, there is little data on TYK-2. Recent work suggests that TYK-2 may play a critical role in the development of a number of inflammatory processes.
Brian, Korniski, Arthur J, Wittwer, Thomas L, Emmons, Troii, Hall, Stacy, Brown, Ann D, Wrightstone, Jeffrey L, Hirsch, Jennifer A, Gormley, Robin A, Weinberg, Joseph W, Leone, Jacqueline E, Day, Jill E, Chrencik, Cynthia D, Sommers, H David, Fischer, Alfredo G, Tomasselli   +14 more
openaire   +2 more sources

Structural basis of Janus kinase trans-activation

Cell Reports, 2023
Naotaka Tsutsumi, Nathanael A Caveney, Caleb R Glassman   +2 more
exaly  

The Development and Use of Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms.

Hematology/Oncology Clinics of North America, 2017
G. Hobbs, Sarah S. Rozelle, A. Mullally
semanticscholar   +1 more source

Janus Kinase Inhibitors and Risk of Venous Thromboembolism: A Systematic Review and Meta-analysis

Mayo Clinic Proceedings, 2021
Jawad Bilal, Irbaz Bin Riaz, Syed Arsalan Ahmed Naqvi   +2 more
exaly  

CircScd1 Promotes Fatty Liver Disease via the Janus Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway

Digestive Diseases and Sciences, 2018
Peifei Li, Keshu Shan, Yi Liu, Yu Zhang, Lu Xu, Lei Xu   +5 more
semanticscholar   +1 more source

Real-world safety and clinical response of Janus kinase inhibitor upadacitinib in the treatment of hidradenitis suppurativa: A retrospective cohort study

Journal of the American Academy of Dermatology, 2022
John Frew
exaly  

Successful therapy for pyoderma gangrenosum with a Janus kinase 2 inhibitor

British Journal of Dermatology, 2018
S. Nasifoglu, B. Heinrich, J. Welzel
semanticscholar   +1 more source

<p>Emerging Role of Janus Kinase Inhibitors for the Treatment of Atopic Dermatitis</p>

ImmunoTargets and Therapy, 2020
Rhea Singh, Courtney E Heron, R I Ghamrawi   +2 more
exaly  

Janus kinase-2 mutation, cirrhosis and splanchnic vein thrombosis

European Journal of Gastroenterology & Hepatology, 2008
COLAIZZO D, AMITRANO L, GUARDASCIONE MA, BALZANO A, MARGAGLIONE, MAURIZIO   +4 more
openaire   +2 more sources

Repigmentation in vitiligo using janus kinase (JAK) inhibitors with phototherapy: systematic review and Meta-analysis

Journal of Dermatological Treatment, 2022
Kevin Phan
exaly