Results 151 to 160 of about 83,254 (357)

Narrow spectrum kinase inhibitors demonstrate promise for the treatment of dry eye disease and other ocular inflammatory disorders [PDF]

, 2018
Doughty, Michael, Foster, Martyn R., Fyfe, Matthew C.T., Hagan, Suzanne, Ofori-Frimpong, Boatemaa, Oliver, Katherine, Rowley, Adele, Sirohi, Sameer, Solanke, Yemisi, Taylor, Mike, Walshe, Claire A., Webber, Steve   +11 more
core   +1 more source

Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome

JPGN Reports, EarlyView.
Abstract We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi‐system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities.
Katherine (Tusia) Pohoreski, Gary Galante, Kiera Pajunen, Marie‐Anne Brundler, Samarjeet Bhandal, Iwona Wrobel   +5 more
wiley   +1 more source

Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma [PDF]

, 2013
Recurrence of Head and Neck Squamous Cell Carcinoma (HNSCC) is common; thus, it is essential to improve the effectiveness and reduce toxicity of current treatments.
Jaseja, Reshma, Jaseja, Reshma
core  

Unravelling the Major Cardiovascular Risks of Systemic Psoriasis Medications: A Literature Systematic Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic inflammatory dermatological condition associated with an elevated risk of cardiovascular events (CVEs). Systemic therapies have transformed disease management, but their cardiovascular (CV) safety profiles remain incompletely understood and inconsistently reported.
Mai Thi Hoai Son, Yves Julien Mbama Biloa, Pauline Gouttefarde, Thomas Franck, Gilles Cizeron, Mathieu Oriol, François Maccari, Elisa Cinotti, Beatrice Trombert‐Paviot, Bienvenu Bongue, Jean‐Luc Perrot   +10 more
wiley   +1 more source

P008 High response rate to Janus Kinase inhibitors after multiple biologic drug failures, across disease indications, in a District General Hospital: results from an audit of the prescribing, safety and efficacy of Janus Kinase inhibitor [PDF]

Alexa Escudero, Sugandh Jain, Nwe Nisoe, Jeremy McNally, Habib Wardak   +4 more
openalex   +1 more source

Constitutive NF-κB Activation Confers Interleukin 6 (IL6) Independence and Resistance to Dexamethasone and Janus Kinase Inhibitor INCB018424 in Murine Plasmacytoma Cells [PDF]

, 2011
Yanqiang Yang, Jason S. Groshong, Hittu Matta, Gopalakrishnan Ramakrishnan, Han Yi, Preet M. Chaudhary   +5 more
openalex   +1 more source

Structure, function and inhibition of poly(ADP-ribose)polymerase, member 14 (PARP14) [PDF]

, 2018
Levonis, Stephan M, Schweiker, Stephanie S, Sherry, Madeleine, Tauber, Amanda   +3 more
core   +1 more source

Safety of Baricitinib for the Treatment of Atopic Dermatitis in Adults Over a Median of 1.6 and up to 4.6 Years Treatment: Final Integrated Analysis of Eight Clinical Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Baricitinib is a selective Janus kinase (JAK)1/JAK2 inhibitor approved in more than 70 countries for the treatment of moderate‐to‐severe atopic dermatitis (AD) in adults, and in over 30 countries for adolescents and children from age 2 years with moderate‐to‐severe AD, who are candidates for systemic therapy.
Antonio Costanzo, Antonio Torrelo, Eric L. Simpson, Marjolein De Bruin‐Weller, Diamant Thaçi, Norito Katoh, Silvia Sabatino, Andrew Buchanan, Kasia Morawska, Samuel Ogwu, Karen Denning, Jonathan I. Silverberg   +11 more
wiley   +1 more source

Resolution of therapy-resistant pyoderma gangrenosum with upadacitinib

JAAD Case Reports, 2023
Lisa Van Eycken, MD, Anne-Catherine Dens, MD, Kurt de Vlam, MD, PhD, Barbara Neerinckx, MD, PhD, Petra De Haes, MD, PhD   +4 more
doaj   +1 more source

Comparative safety of oral Janus kinase inhibitors versus dupilumab in patients with atopic dermatitis: A population-based cohort study [PDF]

Serena Yun‐Chen Tsai, Wanda Phipatanakul, Elena B. Hawryluk, Michiko K. Oyoshi, Lynda C. Schneider, Kevin Sheng‐Kai   +5 more
openalex   +1 more source