Results 251 to 260 of about 74,157 (302)
Efficacy of Janus Kinase Inhibitors in Alopecia in Jordanian Patients: A Retrospective Cohort Study. [PDF]
Aldebei A +7 more
europepmc +1 more source
Therapeutic potential of Janus kinase inhibitors for the management of fibrosis in inflammatory bowel disease. [PDF]
Su J +6 more
europepmc +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Albert Wolkerstorfer +10 more
wiley +1 more source
Optimal use and cycling strategies of Janus kinase inhibitors in ulcerative colitis: current evidence and clinical implications from the KASID Guidelines Task Force Team. [PDF]
Hong SM +19 more
europepmc +1 more source
The Use of Janus Kinase Inhibitors for Primary Neutrophilic Cicatricial Alopecias.
Balfour AN, Osborne S, Mesinkovska NA.
europepmc +1 more source
Janus kinase-1 and Janus kinase-2 inhibitors for treating myelofibrosis
Myelofibrosis is a bone marrow disorder characterized by excessive production of reticulin and collagen fiber deposition caused by hematological and non-hematological disorders. The prognosis of myelofibrosis is poor and treatment is mainly palliative.
Arturo J Martí-Carvajal, Ivan Sola
exaly +5 more sources
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Janus kinase inhibitors: efficacy and safety
Current Opinion in Rheumatology, 2023Purpose of review Janus kinase inhibitors (JAKi) have been available for the treatment of rheumatoid arthritis (RA) since 2012 and are indicated for patients with active disease despite csDMARD therapy. Efficacy and safety, as demonstrated in the clinical trials, was similar to biologics. A recent post marketing trial suggested
Stanley, Cohen, Virginia, Reddy
openaire +2 more sources
Janus kinase inhibitors for alopecia areata
Journal of the American Academy of Dermatology, 2023Janus kinase (JAK) inhibitors have ushered in a new era in alopecia areata (AA). Historically, moderate-to-severe AA was refractory to treatment. JAK inhibitors have changed that; now, treatment of moderate-to-severe AA is possible. Here, we briefly review the history of and rationale for JAK inhibitor treatment of AA, phase 3 clinical trial data, and ...
Brett A, King, Brittany G, Craiglow
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Investigational Janus kinase inhibitors
Expert Opinion on Investigational Drugs, 2013Dysregulation of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway is central to the pathophysiology of myeloproliferative neoplasms (MPN). Small molecule inhibitors of JAK family members are currently under investigation for the treatment of MPN.
Constantine S, Tam, Srdan, Verstovsek
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Efficacy of Janus kinase inhibitors in rheumatoid arthritis
Inflammation Research, 2023Janus kinase inhibitors (JAKis) is a new therapeutic class in autoimmune and inflammatory diseases. Four molecules are approved in rheumatoid arthritis (RA) in Europe. Recently, questions have raised about adverse events. In this context, a synthesis of the efficacy data of JAKis in RA is of use.We performed a literature review based on published ...
Camille, Langbour +3 more
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