Results 271 to 280 of about 55,676 (335)

Interferon-gamma signaling pathway: Modulation of key genes in the progression of glioblastoma. [PDF]

open access: yesWorld J Biol Chem
Oropeza-Martínez E   +6 more
europepmc   +1 more source

Clinical and laboratory presentations of Janus Kinase II-positive patients in Saudi population

open access: diamond, 2014
Hafiz Malhan   +5 more
openalex   +1 more source

Minimal Disease Activity as A New Therapeutic Target in Atopic Dermatitis: A 5‐Year Real‐Life Experience With Dupilumab

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease with significant physical and psychosocial burden. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has proven to be effective for moderate‐to‐severe AD, but long‐term real‐world data remain limited.
Francesco Leo   +11 more
wiley   +1 more source

Initial solid tumor testing (stage 1) of AZD1480, an inhibitor of Janus kinases 1 and 2 by the pediatric preclinical testing program. [PDF]

open access: yesPediatr Blood Cancer, 2014
Houghton PJ   +10 more
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Diversifying the triquinazine scaffold of a Janus kinase inhibitor. [PDF]

open access: yesRSC Med Chem
Mulliri K   +5 more
europepmc   +1 more source

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