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Janus Activated Kinase inhibition in Myelofibrosis
Indian Journal of Cancer, 2012Janus Activated Kinase (JAK) 2 plays an important role in the pathogenesis of myelofibrosis (MF). Ruxolitinib (INCB018424, Jakafi) is a potent dual JAK1 and JAK2 inhibitor. In November 2011, it became approved by the US FDA for the treatment of intermediate or high-risk MF.
openaire +2 more sources
Thromboembolism and Janus Kinase Inhibitors
Drug Safety, 2020Fowzia Ibrahim, David L. Scott
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