Results 71 to 80 of about 5,434,777 (350)

Rational expectations and counter-cyclical monetary policy: the Japanese experience [PDF]

open access: yes
Monetary policy - Japan ; Rational expectations (Economic theory ...
Charles Pigott
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Objects and ideas : Japan and Europe in the nineteenth century [PDF]

open access: yes, 2017
Contacts between nations and countries have always contributed to mutual understanding between peoples and their cultures and customs. It is true of contacts between Japan and the Western world.
Sosnowski, Leszek
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Dragon images in Japanese culture: Genesis and semantics

open access: yesЯпонские исследования
The article deals with the genesis, semantics, and functions of the dragon image in Japanese culture. The relevance of the study is due to the increased attention of researchers to the basic values of local cultures, issues of symbolism, inextricably ...
N. N. Izotova
doaj   +1 more source

Effectiveness of exchange-rate changes on the trade account: the Japanese case [PDF]

open access: yes
Foreign exchange rates - Japan ; Yen, Japanese ; Japan ; Balance of ...
Kenneth Bernauer
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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