Results 91 to 100 of about 3,279,442 (393)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Features of ecology for bivalve mollusk Potamocorbula amurensis in Peter the Great Bay, Japan Sea

open access: yesИзвестия ТИНРО
Features of ecology are considered for euryhaline bivalve mollusk Potamocorbula amurensis dwelling in Peter the Great Bay. Spatial distribution of the species is not uniform, the mollusks settle mainly in the areas affected to the river discharge ...
E. V. Kolpakov   +2 more
doaj   +1 more source

The Straits of Malacca: Regional powers vis-a-vis littoral states in strategic and security issues and interests [PDF]

open access: yes, 2010
This paper presents an overview of the strategic and security issues surrounding the Straits of Malacca. It begins by introducing the strategic nature of the Straits of Malacca and piracy threat in the busy sea lane. Subsequently this paper discusses the
Ismail, Siti Zubaidah   +1 more
core  

Precise Measurements of Atmospheric Muon Fluxes with the BESS Spectrometer

open access: yes, 2002
The vertical absolute fluxes of atmospheric muons and muon charge ratio have been measured precisely at different geomagnetic locations by using the BESS spectrometer.
A Moiseev   +66 more
core   +2 more sources

Environmental DNA as a ‘Snapshot’ of Fish Distribution: A Case Study of Japanese Jack Mackerel in Maizuru Bay, Sea of Japan

open access: yesPLoS ONE, 2016
Recent studies in streams and ponds have demonstrated that the distribution and biomass of aquatic organisms can be estimated by detection and quantification of environmental DNA (eDNA).
Satoshi Yamamoto   +24 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Tectonics of sedimentary basins in and around Japan since the opening of the Sea of Japan

open access: yesChishitsugaku zasshi, 2018
The opening of the Sea of Japan, associated with detachment of the Japan Arc from the Asian Continent, was the most significant Cenozoic event in Japan.
T. Nakajima
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

The Delimitation of East China Sea Continental Shelf:Sino-Japanese Disputes from the Perspective of International Law [PDF]

open access: yes
The East China Sea which covers a total area of 750,000 square kilometers is a semi-closed sea lying between the eastern coast of Chinas mainland and the Pacific Ocean, bounded on the west by China, on the east by the Kyushu and the Ryukyu Islands of ...
Zhu Fenglan
core   +1 more source

PICES Press, Vol. 5, No. 2, July 1997 [PDF]

open access: yes, 1997
WG 10 Fukuoka Workshop Pacific salmon:climate-linked long-term stock fluctuations The state of the eastern North Pacific in the second half of 1996 The state of the western North Pacific in the second half of 1996 The status of the Bering Sea in ...

core  

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