Results 61 to 70 of about 3,749,304 (354)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Japanese Attitudes Toward American Business Involvement in Japan: an Empirical Investigation [PDF]
Examines Japanese attitudes and behavioral intentions toward US products, firms, and government. Findings indicate that, although Japanese consumers do not regard US products as better than competing Japanese products, they still tend to purchase them ...
Akhter, Syed, Hamada, Toshikazu
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Japanese Model of Attracting Foreign Youth in the Higher Education System
Introduction. National education and science systems are increasingly integrated into the international scientific and educational space in the context of increasing globalisation.
S. V. Ryazantsev +2 more
doaj +1 more source
Repairing Tales from Japan: Changes Over Time in Personal Narratives [PDF]
At two different times, Time 1 and Time 2, 13 participants in Japan (8 Japanese and 5 Americans) were asked to spontaneously respond in English to this prompt: "Tell me about one of the most exciting or dangerous moments in your life." The Japanese ...
Riney, Timothy
core +2 more sources
CLDN18.2 expression is highly prevalent in Japanese patients with gastric cancer, making it a targetable alteration, and supporting development of zolbetuximab as a therapeutic agent for this patient population.
C. Rohde +5 more
semanticscholar +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Colorectal cancer is a major cause of death in Japan, where it accounts for the largest number of deaths from malignant neoplasms among women and the third largest number among men. Many new methods of treatment have been developed during recent decades.
Toshiaki Watanabe +34 more
semanticscholar +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The gut microbiome of healthy Japanese and its microbial and functional uniqueness
The human gut microbiome has profound influences on the host's health largely through its interference with various intestinal functions. As recent studies have suggested diversity in the human gut microbiome among human populations, it will be ...
Suguru Nishijima +6 more
semanticscholar +1 more source

