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Japanese Encephalitis, Singapore
To the Editor: Japanese encephalitis (JE) is an endemic flavivirus disease in Asia. The JE virus (JEV) is one of the leading causes of viral encephalitis: 35,000–50,000 cases occur every year (1). While most infections are subclinical, the disease has a high case-fatality rate (≈25%) and considerable incidence of serious neurologic sequelae with the ...
Yin-Ling Koh+5 more
doaj +3 more sources
RNA viruses are not only reported for viral pandemics but also as important agents for emerging/re-emerging diseases. Japanese encephalitis virus (JEV) is reported to cause epidemics of encephalitis in Southeast Asia, India, Korea, China, and Indonesia.
Banani Poddar+3 more
openaire +4 more sources
Safety of Japanese encephalitis vaccines [PDF]
Japanese encephalitis (JE) is an endemic disease dominantly in the Asia-Pacific region with mortality rate varying between 3% and 30%. Long-term neuropsychiatric sequelae developed in 30-50% of the survivors. There is no available antiviral therapy for JE. JE vaccines play a major role in preventing this devastating disease.
Ping-Ing Lee, Ya-Li Hu
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Japanese Encephalitis Vaccines [PDF]
As an eminently vaccine-preventable disease, encephalitis caused by Japanese encephalitis virus (JEV) has attracted an unusually high degree of attention from those seeking to develop viral vaccines. Since the 1950s, all types of JEV vaccines including inactivated, recombinant and live attenuated ones have been licensed.
openaire +3 more sources
Background In Southeast Asia, dengue viruses often co-circulate with other flaviviruses such as Japanese encephalitis virus, and due to the presence of shared antigenic epitopes it is often difficult to use serological methods to distinguish between ...
Sum Magdline+3 more
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Epidemiology of Japanese encephalitis in the Philippines prior to routine immunization
Background: Findings were published in 2015 that highlighted the endemicity of Japanese Encephalitis (JE) in the Philippines. The policymakers responded by conducting an immunization campaign and strengthening the surveillance system.
Anna Lena Lopez+6 more
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Japanese encephalitis is the main cause of viral encephalitis in Asia. In a previous single-arm vaccine trial, an inactivated chromatographically purified Japanese encephalitis Vero cell vaccine (CVI-JE; JEVACTM) was safe and immunogenic in 152 Thai ...
Weerawan Hattasingh+10 more
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The reemerging and outbreak of genotypes 4 and 5 of Japanese encephalitis virus
The Japanese encephalitis virus (JEV) is classified into five distinct genotypes, with genotypes 1 and 3 historically showing higher activity. These genotypes are the primary agents of viral encephalitis in the Asian continent.
Weijia Zhang+3 more
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The increasing trend of mosquito-borne pathogens demands more accurate global estimations of infection and transmission risks between mosquitoes. Here, we systematically review field and laboratory studies to assess the natural field infection and ...
María José Tolsá-García+3 more
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