Results 11 to 20 of about 246,780 (358)
JC Virus Granule Cell Neuronopathy and Lymphoma. [PDF]
Open Forum Infect Dis, 2018 Abstract Neurological opportunistic infections are going to increase. Clinicians should be aware of the neurological spectrum of JC virus manifestations, including granule cell neuronopathy. Detection of JC virus DNA by polymerase chain reaction in cerebrospinal fluid should be realized in the assessment of a progressive cerebellar ...
Demas A +5 more
europepmc +5 more sources
Progressive multifocal leukoencephalopathy in a patient without apparent immunosuppression [PDF]
Virology Journal, 2010 An 80-year-old man with no history of an immune-compromising disorder was diagnosed with progressive multifocal leukoencephalopathy (PML). He presented with dysphagia and left-sided weakness; magnetic resonance imaging demonstrated marked signal ...
Escobar Miguel A +4 more
doaj +5 more sources
JC Virus Infection of the Brain [PDF]
American Journal of Neuroradiology, 2010 Since its initial description, there have been significant changes in the epidemiology, pathogenesis, and clinical and imaging manifestations of JCV infection of brain. The most common clinical manifestation is PML. Other recently described CNS manifestations are JCE, JCVGCN, and JCM.
Joel K. Curé +4 more
openaire +3 more sources
JC Virus: An oncogenic virus in animals and humans? [PDF]
Seminars in Cancer Biology, 2009 JC virus (JCV) is a human polyomavirus of the Polyomaviridae family, which also includes BK virus and simian vacuolating virus 40 (SV40). JC virus was first isolated in 1971 from the brain of a patient with Progressive Multifocal Leukoencephalopathy (PML). Like other polyomaviruses, JCV has a restricted host range. The virus infects the majority of the
Walter J. Atwood, Melissa S. Maginnis
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Brain tumors of owl monkeys inoculated with JC virus contain the JC virus genome [PDF]
Journal of Virology, 1984 The DNA from astrocytomas that developed in adult owl monkeys 16 to 36 months after intracranial inoculation with JC virus (JCV) was examined for the presence of the JCV genome by hybridization to cloned JCV DNA. The JCV genome was found to be integrated into the cellular DNA in all tumors examined.
Duard L. Walker +5 more
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Quasispecies analysis of JC virus DNA present in urine of healthy subjects. [PDF]
PLoS ONE, 2013 JC virus is a human polyomavirus that infects the majority of people without apparent symptoms in healthy subjects and it is the causative agent of progressive multifocal leucoencephalopathy (PML), a disorder following lytic infection of oligodendrocytes
Tom Van Loy +3 more
doaj +1 more source
T' Proteins Influence JC Virus Biology [PDF]
Journal of Neurovirology, 2003 The JC virus early mRNA is alternatively spliced to yield five transcripts that encode large T antigen, small t antigen, T'(135), T'(136), and T'(165). The splicing process is regulated differentially in transformed versus lytically infected cells and temporally during the course of a productive infection. The authors have identified a potential exonic
Brigitte Bollag +3 more
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Patch formation driven by stochastic effects of interaction between viruses and defective interfering particles [PDF]
PLoS Comput Biol 19(10), 2023, 2023 Defective interfering particles (DIPs) are virus-like particles that occur naturally during virus infections. These particles are defective, lacking essential genetic materials for replication, but they can interact with the wild-type virus and potentially be used as therapeutic agents.
arxiv +1 more source
Development of a Potent Stabilizer for Long-Term Storage of Foot-and-Mouth Disease Vaccine Antigens
Vaccines, 2021 A local virus isolate, O/SKR/JC/2014 (O JC), has been considered as a candidate vaccine strain in the development of a domestic foot-and-mouth disease (FMD) vaccine in Korea.
Ah-Young Kim +7 more
doaj +1 more source
JC Virus Agnoprotein Colocalizes with Tubulin [PDF]
Journal of Neurovirology, 2003 The human polyomavirus JC (JCV) encodes an agnoprotein that consists of 71 amino acid residues, with a molecular weight of approximately 8 kDa, from the late protein coding region. The agnoprotein of JCV shares 50% to 60% homology with those of simian virus 40 (SV40) and BK virus (BKV), and the carboxyl-terminal region of JCV agnoprotein is relatively ...
Shuichi Endo +6 more
openaire +3 more sources