Results 21 to 30 of about 65,609 (259)
Reactivation of human herpesvirus-6 in natalizumab treated multiple sclerosis patients. [PDF]
PLoS ONE, 2008 The alpha(4) integrin antagonist natalizumab was shown to be effective in patients with immune-mediated disorders but was unexpectedly associated with JC polyomavirus associated progressive multifocal leukoencephalopathy (PML) in two multiple sclerosis ...
Karen Yao +9 more
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Brain tumors of owl monkeys inoculated with JC virus contain the JC virus genome [PDF]
Journal of Virology, 1984 The DNA from astrocytomas that developed in adult owl monkeys 16 to 36 months after intracranial inoculation with JC virus (JCV) was examined for the presence of the JCV genome by hybridization to cloned JCV DNA. The JCV genome was found to be integrated into the cellular DNA in all tumors examined.
N R, Miller +5 more
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Revista de Saúde Pública, 1977 A total of 173 sera from isolated Brazilian Indian populations, 39 from the Diauarun area, and 68 from the Alto Xingú area, respectively in the North and the South of the Xingú National Park and 66 Kren-Akorore Indians, were examined for hemagglutination
J. A. N. Candeias +3 more
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JRSM Open, 2023 Progressive multifocal leukoencephalopathy (PML) is a rare disease of the central nervous system caused by opportunistic infection with JC virus. It presents in patients who are immunocompromised, and diagnosis is made by correlating clinical findings ...
Sabrina Grant +4 more
doaj +1 more source
Progressive multifocal leukoencephalopathy: new concepts
Arquivos de Neuro-Psiquiatria, 2013 Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the CNS caused by reactivation of JC virus (JCV) in a setting of cellular immunosuppression.
Marco A. Lima
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JC polyoma virus and kidney disease [PDF]
Kidney International, 2014 To the Editor: In a recent article, Divers et al.1 describe the interaction between apolipoprotein L1 (APOL1) genotypes and JC viruria, and their relationship with nondiabetic nephropathy in African Americans. The authors found that in African Americans with two APOL1 risk alleles, the prevalence of kidney disease was lower for those with JC viruria ...
Ana P, Rossi +2 more
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Human polyomavirus JC virus genome [PDF]
Journal of Virology, 1984 The complete DNA sequence of the human JC virus, which was found to consist of 5,130 nucleotide pairs, is presented. The amino acid sequence of six proteins could be deduced: the early, nonstructural proteins, large T and small t antigens; the late capsid proteins, VP1, VP2, and VP3; and the agnogene product encoded within the late leader sequence ...
R J, Frisque, G L, Bream, M T, Cannella
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JC Virus Agnoprotein Colocalizes with Tubulin [PDF]
Journal of Neurovirology, 2003 The human polyomavirus JC (JCV) encodes an agnoprotein that consists of 71 amino acid residues, with a molecular weight of approximately 8 kDa, from the late protein coding region. The agnoprotein of JCV shares 50% to 60% homology with those of simian virus 40 (SV40) and BK virus (BKV), and the carboxyl-terminal region of JCV agnoprotein is relatively ...
Shuichi, Endo +6 more
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Journal of Global Infectious Diseases, 2016 Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by polyomavirus John Cunningham (JC) virus.
Tanmay S Panchabhai +4 more
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Case Reports in Oncology, 2011 We describe a case of progressive multifocal leukoencephalopathy (PML) caused by infection with the human polyomavirus JC virus in a patient with B-cell small lymphocytic leukemia who was treated with rituximab.
Subhankar Chakraborty +5 more
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